Publications by authors named "Aminah A Barqawi"

Article Synopsis
  • - The study investigates using CRISPR-Cas9 technology to target and inhibit the mutant Androgen Receptor (AR) gene responsible for spinal bulbar muscular atrophy (SBMA), a neurodegenerative disorder.
  • - Researchers designed specific guided RNAs (gRNAs) targeting the AR gene that show high efficiency, accurate matching, and minimal off-target effects, suggesting they could be effective for gene editing.
  • - The findings indicate a promising potential for CRISPR-Cas9 as a therapeutic option for SBMA, advocating for further research to evaluate its effectiveness in preclinical and clinical settings.
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Aloe barbadensis is a stemless plant with a length of 60-100 cm with juicy leaves which is used for its remedial and healing properties in different suburbs of various countries. The present study was conducted to investigate the effect of A. barbadensis leaf extract (aqueous and ethanolic) in yeast induced pyrexia and acetic acid induced writhing in rat model to evaluate the antipyretic biomarkers and its phytochemical screening with computational analysis.

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This study aims to detect salt stress-related genes and mechanisms of the wild barley . Among the generated RNA-Seq datasets, several regulated transcripts are influenced by levels of cellular carbon, nitrogen and oxygen. Some of the regulated genes act on photorespiration and ubiquitination processes, as well as promoting plant growth and development under salt stress.

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(or the miracle tree) is a wild plant species widely grown for its seed pods and leaves, and is used in traditional herbal medicine. The metagenomic whole genome shotgun sequencing (mWGS) approach was used to characterize antibiotic resistance genes (ARGs) of the rhizobiomes of this wild plant and surrounding bulk soil microbiomes and to figure out the chance and consequences for highly abundant ARGs, e.g.

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Since ancient times, seaweeds have been employed as source of highly bioactive secondary metabolites that could act as key medicinal components. Furthermore, research into the biological activity of certain seaweed compounds has progressed significantly, with an emphasis on their composition and application for human and animal nutrition. Seaweeds have many uses: they are consumed as fodder, and have been used in medicines, cosmetics, energy, fertilizers, and industrial agar and alginate biosynthesis.

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Legumes are an imperative source of food and proteins across the globe. They also improve soil fertility through symbiotic nitrogen fixation (SNF). Genome editing (GE) is now a novel way of developing desirable traits in legume crops.

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