The search for bacteria-labeling agents that are more efficient and less toxic compared to existing staining dyes is ongoing. Fluorescent quantum dots and carbon dots (CDs) have been extensively researched for various bioimaging applications. Priority is given to CDs due to several advantages, including lower toxicity, versatility in tuning their properties, and better photostability compared to metal-based quantum dots.
View Article and Find Full Text PDFThe development of interprofessional teams in primary care presents opportunities for social workers to take on new leadership positions. This study seeks to describe how social workers engaged in leadership roles in primary care during the COVID-19 pandemic. A cross-sectional on-line survey was disseminated to primary care social workers across Ontario, Canada, with a total of 159 respondents.
View Article and Find Full Text PDFBackground: Canadian youth (aged 16-24) have the highest rates of mental health and addiction concerns across all age groups and the most unmet health care needs. There are many structural barriers that contribute to the unmet mental health care needs of youth including lack of available and appropriate services, high costs, long wait times, fragmented and siloed services, lack of smooth transition between child and adult services, stigma, racism, and discrimination, as well as lack of culturally appropriate treatments. Levesque et al.
View Article and Find Full Text PDFObjectives: There have been concerns about the adverse effects of the COVID-19 pandemic on Canadian youth (aged 16-24) as they have the highest rates of mental health concerns. The objectives of the present study were to explore the experiences of youth with mental health and/or addiction concerns and their families during the pandemic, and to examine how adequate and equitable mental health services have been for youth and families from the perspectives of youth, parents, and service providers.
Methods: Using a descriptive qualitative research design and a university-community partnership, we conducted individual interviews with youth, parents, and service providers.
Leadership skills are a critical component of effective social work practice in interdisciplinary healthcare and mental healthcare settings. Over the last two decades there has been increased attention to the importance of social work leadership skills for clinical practice. Moreover, social workers display essential leadership skills when supporting individuals and communities amid large-scale crises such as pandemics, natural disasters, wars, and other sociopolitical crises.
View Article and Find Full Text PDFIn our study, waste parts of Litchi chinensis cultivar Surakhi were selected for the production of silver nanoparticles. Qualitative and quantitative analysis revealed peel extracts rich in alkaloids, flavonoids, saponins, steroids, phenolics, tannins as compared to seed extracts. Two different types of nanoparticles (PAN and PMN) were prepared from Litchi chinensis peel using crude aqueous and methanolic extracts.
View Article and Find Full Text PDFIn present study, diverse -mediated nanostructures in combination with 5-fluorouracil drug were fabricated viz. Au, Se, Ag, Ag-Se, Ag-Au, 5-FU Ag-Se and 5-FU Ag-Au with subsequent characterization and scrutinization of their anticarcinogenic capabilities. UV-Visible spectroscopic analysis confirmed the state transition for each precursor salt.
View Article and Find Full Text PDFIntroduction: The COVID-19 pandemic has brought tremendous changes in healthcare delivery and exacerbated a wide range of inequities. Social workers across a broad range of healthcare settings bring an expertise in social, behavioural and mental healthcare needed to help address these health inequities. In addition, social workers integrate policy-directed interventions and solutions in clinical practice, which is a needed perspective for recovery from the COVID-19 pandemic.
View Article and Find Full Text PDFIfosfamide is a widely used chemotherapeutic agent having broad-spectrum efficacy against several tumors. However, nephro, hepato, neuro cardio, and hematological toxicities associated with ifosfamide render its use limited. These side effects could range from organ failure to life-threatening situations.
View Article and Find Full Text PDFIntroduction: Leadership skills are an integral part of effective social work practice in health and mental healthcare settings. Social workers require critical leadership skills to effectively support, treat and advocate for the complex needs of those most vulnerable. Despite an increasing focus on social work leadership within the last decade, there has been a paucity of research on social work leadership competencies within the realm of health and mental health service provision.
View Article and Find Full Text PDFIntroduction: Social work is a key profession in the field of mental health worldwide and the profession has values that are aligned with a recovery paradigm. However, there are gaps in understanding how social workers are applying the recovery paradigm in practice. This study will scope and synthesise the literature related to recovery and social work practice in mental health and addictions.
View Article and Find Full Text PDFCisplatin is amongst the most potent chemotherapeutic drugs with applications in more than 50% of cancer treatments, but dose-dependent side effects limit its usefulness. L. () has a proven role in several therapeutic applications in the traditional medicinal system.
View Article and Find Full Text PDFTo evaluate differences between male patients in secure psychiatric settings in the UK based on whether they are detained under civil or forensic sections of the Mental Health Act 1983. A cohort of patients discharged from a secure psychiatric hospital were evaluated for length of stay and frequency of risk-related incidents. Overall, 84 patients were included in the study: 52 in the forensic group and 32 in the civil group.
View Article and Find Full Text PDFAntisocial personality disorder (ASPD) often presents with highly impulsive, violent behavior, and pathological changes in the orbitofrontal cortex (OFC) and ventral striatum (VS) are implicated. Several compelling reasons support a relationship between low monoamine oxidase-A (MAO-A), an enzyme that regulates neurotransmitters, and ASPD. These include MAO-A knockout models in rodents evidencing impulsive aggression and positron emission tomography (PET) studies of healthy subjects reporting associations between low brain MAO-A levels and greater impulsivity or aggression.
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