Mucoadhesive Enhancement of Gelatine by Tannic Acid Crosslinking for Buccal Application.

This study aims to evaluate the impact of formulation parameters on tannic acid-crosslinked gelatine (GelTA) films, intended as a mucoadhesive matrix for extended buccal drug delivery. GelTA films were prepared using the solvent evaporation technique and screened based on their mucoadhesive and dissolution characteristics. The formulation variables included the source of gelatine (bovine and fish), tannic acid concentration, pH of the film-forming solutions, and the type and concentration of plasticisers.

A review: Gelatine as a bioadhesive material for medical and pharmaceutical applications.

Bioadhesive polymers offer versatility to medical and pharmaceutical inventions. The incorporation of such materials to conventional dosage forms or medical devices may confer or improve the adhesivity of the bioadhesive systems, subsequently prolonging their residence time at the site of absorption or action and providing sustained release of actives with improved bioavailability and therapeutic outcomes. For decades, much focus has been put on scientific works to replace synthetic polymers with biopolymers with desirable functional properties.

Sun Protective Potential and Physical Stability of Herbal Sunscreen Developed from Afghan Medicinal Plants.

Objectives: The aim of this study was to develop an herbal topical sunscreen formulation based on some fixed oils in combination with some medicinal plants.

Materials And Methods: The crude and purified extracts were screened for their phytochemical profile and their sun protection potentials. Based on our results, purified extract (EAPE), sesame oil, and sea buckthorn oil were selected for the development of the sunscreen formulation.