Publications by authors named "Amilcar Silva Dos Santos"

Background: Repetitive transcranial magnetic stimulation (rTMS) has been increasingly used for treating obsessive-compulsive disorder (OCD). Although several meta-analyses have explored its effectiveness and safety, there is no umbrella review specifically focused on rTMS for OCD. This umbrella review followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and analyzed relevant meta-analyses on rTMS for OCD.

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Introduction: Neuroleptic malignant syndrome (NMS), thought to arise through dopamine antagonism, is life-threatening. While prompt diagnosis of NMS is critical, it may be obscured by other diagnoses, such as malignant catatonia, with overlapping, life-threatening symptoms. Initiation of dopamine-blocking agents such as antipsychotics and abrupt cessation of dopaminergic medications such as amantadine can precipitate NMS.

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Direct communication between different nervous systems has been recently reported through Brain-to-Brain-Interfaces and brainet. Closed loops systems between the brain and the spinal cord from the same individual have also been demonstrated. However, the connection between different nervous systems through the spinal cord has not yet been considered.

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We report a case of a 61-year-old woman who presented with acute psychosis as a major manifestation of Legionnaires' disease in the absence of other neuropsychiatric symptoms. Clinical history revealed dry cough and nausea. Observation showed fever and auscultation crackles in the lower lobe of the right lung.

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Article Synopsis
  • Anti-NMDA receptor encephalitis is an autoimmune condition characterized by symptoms affecting psychiatric, neurological, and autonomic functions, caused by autoantibodies targeting NMDA receptors and sometimes linked to tumors like ovarian teratomas.
  • A case is highlighted involving a 15-year-old girl who experienced first-episode psychosis along with severe psychiatric and neurological symptoms, which improved with immunotherapy and psychiatric treatment.
  • The case emphasizes the importance of recognizing this newly identified disease in clinical settings, particularly to avoid misdiagnosis in children and adolescents who might present with functional psychiatric symptoms.
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Article Synopsis
  • * Out of 32 patients analyzed, none had neuroimaging findings that were directly responsible for their psychotic symptoms; some had unrelated incidental findings.
  • * The results imply that while neuroimaging is generally not necessary for first-episode psychosis, it may be beneficial in cases with additional neurological signs or atypical presentations.
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