The linear excisional wound: an improved model for human ex vivo wound epithelialization studies.

Background/purpose: Wound healing is a complex process that involves multiple intercellular and intracellular processes and extracellular interactions. Explanted human skin has been used as a model for the re-epithelialization phase of human wound healing. The currently used standard technique uses a circular punch biopsy tool to make the initial wound.

Personalizing dermatology: the future of genomic expression profiling to individualize dermatologic therapy.

At the start of the 21st century, the human genome project provided the scientific community with an enormous array of information as genetic blueprints. A landmark period, yet its potential contribution to medicine at the time was limited and unknown. However, with new technological advances, the benefits of identifying genomic profiles became apparent.