Publications by authors named "Amiirah Bibi Edoo"
Nucleic Acids Res
November 2017
Article Synopsis
- Prolyl isomerases, like FKBP25, have a key role in converting proline residues between cis and trans configurations, but they also have additional domains that enhance their functionality.
- The N-terminal basic tilted helix bundle (BTHB) domain of FKBP25 binds specifically to double-stranded RNA (dsRNA), distinguishing it from DNA and single-stranded RNA.
- This RNA binding is crucial for FKBP25's localization in the nucleolus and facilitates interactions with pre-ribosomes and early ribosome biogenesis factors, showcasing the multifunctional nature of prolyl isomerases in cellular processes.
