Publications by authors named "Ami Isshiki"
We aimed to develop machine learning-based predictive models for identifying inappropriate implantable cardioverter-defibrillator (ICD) therapy. Our study included 182 consecutive cases (average age 62.2 ± 4.
View Article and Find Full Text PDFObjective: Factors such as age, vital signs, renal function, Killip class, cardiac arrest, elevated cardiac biomarker levels, and ST deviation predict survival in patients with acute myocardial infarction (AMI). However, the existing risk assessment tools lack comprehensive consideration of catheter-related factors, and short-term prognostic predictors are unknown. This study aimed to clarify in-hospital prognostic predictors in hospitalized patients with AMI.
View Article and Find Full Text PDFBackground: Coronary healed plaques (HPs) reportedly have high vulnerability or show advanced atherosclerosis and a risk of rapid plaque progression. However, the prognosis of stable angina pectoris (SAP) patients with HPs undergoing percutaneous coronary intervention (PCI) remains under-investigated.
Methods and results: We analyzed 417 consecutive lesions from SAP patients undergoing pre- and post-intervention optical coherence tomography (OCT) for which HPs were defined as having a layered appearance.
Optical coherence tomography and coronary angioscopy assessment of healed coronary plaque components.
Int J Cardiovasc Imaging
October 2021
Article Synopsis
- The study focuses on understanding the characteristics of healed plaques (HPs) in patients with coronary artery lesions using advanced imaging techniques like optical coherence tomography (OCT) and coronary angioscopy (CAS).
- Out of 33 patients, HPs were identified in 52.8% of lesions, which showed more severe conditions, such as worse blood flow and higher blockage than lesions without HPs.
- The presence of specific features like thin-cap fibroatheroma, macrophages, and red thrombus significantly predicted HPs and suggested that these healed lesions may still carry risks for future heart problems due to underlying inflammation.
Purpose: Eicosapentaenoic acid (EPA) has been reported to augment endothelial function and improve clinical outcomes in patients with coronary artery disease (CAD). The purpose of this study was to determine whether EPA could improve residual endothelial dysfunction despite adequate lipid-lowering with statin in CAD patients.
Methods: Eighty patients with established CAD, who had been on statin treatment and had serum low-density lipoprotein cholesterol (LDL-C) levels <100 mg/dl, were randomly assigned to receive either 1,800 mg of EPA daily plus statin (EPA group, n = 40) or statin alone (Control group, n = 40).
Background: How coronary distensibility contributes to stable or unstable clinical manifestations remains obscure. We postulated that the heterogeneous plaque distensibility is associated with unstable clinical presentations in patients with acute coronary syndrome (ACS).
Methods And Results: Seventeen and 19 ACS-related and -unrelated lesions, respectively, were visualized using intravascular ultrasound imaging with simultaneous intracoronary pressure recording.