miR-199a-3p suppresses neuroinflammation by directly targeting MyD88 in a mouse model of bone cancer pain.

Aims: Pain is a profoundly debilitating symptom in cancer patients, leading to disability, immobility, and a marked decline in their quality of life. This study aimed to investigate the potential roles of miR-199a-3p in a murine model of bone cancer pain induced by tumor cell implantation in the medullary cavity of the femur.

Materials And Methods: We assessed pain-related behaviors, including the paw withdrawal mechanical threshold (PWMT) and the number of spontaneous flinches (NSF).

Team Strategies and Tools to Enhance Performance and Patient Safety at primary healthcare units: Effect on patients' outcomes.

The purpose of this study was to examine the effect of application of team strategies and tools to enhance performance and patient safety at primary healthcare units on patients' safety and outcomes. Team Strategies and Tools to Enhance Performance and Patient Safety (Team STEPPS) are specially intended to enhance patient safety through effective communication and teamwork skills. To examine, a quasi-experimental (pre-posttest) design was utilized.

Oxford Textbook of Palliative Nursing. 5th revised edition.

[No Abstract Available].