Wilson's disease causes copper accumulation in the liver and extrahepatic organs. The available therapies aim to lower copper levels by various means. However, a potent drug that can repair the damaged liver and brain tissue is needed.
View Article and Find Full Text PDFJ Back Musculoskelet Rehabil
January 2023
Background: Inclined walking is associated with multiple musculoskeletal benefits and is considered a therapeutic exercise. Various patterns of increased and decreased muscle activation with inclined surfaces have been observed in normal muscles, with more focus on the proximal lower limb musculature.
Objective: The aim of this study was to assess the differences in electromyographic activation of gastrocnemius, soleus, and tibialis anterior at various inclined surfaces during gait.
Micro-crack formation and resultant bacterial infiltration are major causes of secondary caries formation in dental resin-based composite restorations. Improving dental resin composites’ mechanical and biological properties using highly bendable nanoparticles (NPs) can resolve this issue. This study aims to develop novel Diethylaminoethyl (DEAE)-Dextran silver nanoparticles (AgNPs) and subsequently modify composite resins with these NPs to enhance their mechanical and antibacterial properties.
View Article and Find Full Text PDFStroke is a cerebrovascular disease (CVD), which results in hemiplegia, paralysis, or death. Conventionally, a stroke patient requires prolonged sessions with physical therapists for the recovery of motor function. Various home-based rehabilitative devices are also available for upper limbs and require minimal or no assistance from a physiotherapist.
View Article and Find Full Text PDFIntramuscular electromyography (iEMG) signals, invasively recorded, directly from the muscles are used to diagnose various neuromuscular disorders/diseases and to control rehabilitative and assistive robotic devices. iEMG signals are potentially being used in neurology, kinesiology, rehabilitation and ergonomics, to detect/diagnose various diseases/disorders. Electromyography-based classification and analysis systems are being designed and tested for the classification of various neuromuscular disorders and to control rehabilitative and assistive robotic devices.
View Article and Find Full Text PDFPurpose: It is estimated that every year, 1 × 10(6) women are diagnosed with breast cancer, and more than 410,000 die annually worldwide. Digital Image Elasto Tomography (DIET) is a new noninvasive breast cancer screening modality that induces mechanical vibrations in the breast and images its surface motion with digital cameras to detect changes in stiffness. This research develops a new automated approach for diagnosing breast cancer using DIET based on a modal analysis model.
View Article and Find Full Text PDFPurpose: Breast cancer is a major public health issue for women, and early detection significantly increases survival rate. Currently, there is increased research interest in elastographic soft-tissue imaging techniques based on the correlation between pathology and mechanical stiffness. Anthropomorphic breast phantoms are critical for ex vivo validation of emerging elastographic technologies.
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