Comprehensive evaluation of deep learning architectures for prediction of DNA/RNA sequence binding specificities.

Motivation: Deep learning architectures have recently demonstrated their power in predicting DNA- and RNA-binding specificity. Existing methods fall into three classes: Some are based on convolutional neural networks (CNNs), others use recurrent neural networks (RNNs) and others rely on hybrid architectures combining CNNs and RNNs. However, based on existing studies the relative merit of the various architectures remains unclear.

An Ensemble Feature Selection Method for Biomarker Discovery.

Feature selection in Liquid Chromatography-Mass Spectrometry (LC-MS)-based metabolomics data (biomarker discovery) have become an important topic for machine learning researchers. High dimensionality and small sample size of LC-MS data make feature selection a challenging task. The goal of biomarker discovery is to select the few most discriminative features among a large number of irreverent ones.