Simulation of transvascular transport of nanoparticles in tumor microenvironments for drug delivery applications.

Nanomedicine is a promising approach for tumor therapy but penetration is challenged by complex tumor microenvironments. The purpose of this study is to design nanoparticles and analyze their transport in two abnormal microenvironments through a 2-D simulation. Employing a Computational Fluid Dynamics (CFD) approach, tumor vascular-interstitial models were initially simulated, and the impact of nanoparticles on the velocity profile and pressure gradient within the tumor microenvironment was observed.

A computer vision-based system for recognition and classification of Urdu sign language dataset.

Human beings rely heavily on social communication as one of the major aspects of communication. Language is the most effective means of verbal and nonverbal communication and association. To bridge the communication gap between deaf people communities, and non-deaf people, sign language is widely used.

Global COVID-19 Vaccine Acceptance: A Systematic Review of Associated Social and Behavioral Factors.

COVID-19 vaccines have met varying levels of acceptance and hesitancy in different parts of the world, which has implications for eliminating the COVID-19 pandemic. The aim of this systematic review is to examine how and why the rates of COVID-19 vaccine acceptance and hesitancy differ across countries and continents. PubMed, Web of Science, IEEE Xplore and Science Direct were searched between 1 January 2020 and 31 July 2021 using keywords such as "COVID-19 vaccine acceptance".