The emergence and spread of methicillin-resistant Staphylococcus aureus (MRSA) in hospitals is a major global public health concern. The current study sought to characterize 25 MRSA clinical isolates collected in a Tunisian hospital from December 2015 to September 2016, with the genetic lineages, virulence factors, and antibiotic resistance mechanisms determined for these isolates. Three spa-types were detected: t037 (23 isolates), t932, and t2235 (one isolate each).
View Article and Find Full Text PDFMethicillin-resistant Staphylococcus aureus (MRSA) is an important pathogen causing health care-infections in the world, especially in burns. The aim of this study was to assess the extent of dissemination of MRSA isolated from burn patients in Burn Intensive Care Unit in Tunisia and to evaluate the frequency of virulence and antibiotics resistance genes. Among the 72 S.
View Article and Find Full Text PDFBackground: Carbapenemase-producing Enterobacterales (CPE) present a threat to public health worldwide.
Aim: To study their prevalence at the Trauma and Burn Center's Burn Unit and investigate their molecular characteristics and their associated antibiotics resistance patterns.
Methods: This is a retrospective study conducted at the Trauma and Burn Center's laboratory between july 2017 and december 2018.
Extensively drug resistant Acinetobacter baumannii (XDR-Ab), has emerged as an important pathogen in several outbreaks. The aim of our study was to investigate the eventual genetic relatedness of XDR-Ab strains recovered from burn patients and environment sites in the largest Tunisian Burn Intensive Care Unit (BICU) and to characterize β-lactamase encoding genes in these strains. Between March 04th, 2019 and April 22nd, 2019 an outbreak of XDR-Ab was suspected.
View Article and Find Full Text PDFBackground: Continuous monitoring of the bacterial flora and antibiotic resistance of the main bacteria involved in nosocomial infections helps improve treatment and prevention strategies.
Aim: To compare the bacteriological profile and antibiotic susceptibility of the main bacterial isolates within the burned patients over two periods of 3 years and in two hospitals.
Methods: During two three-year periods: period 1 (P1): 1/7/2005-30/6/2008 and period 2 (P2): 1/7/2008-30/6/2011) and in two hospitals: Hospital Aziza Othmana (HAO) and the traumatology and burn center (CTGB), 2153 and 3719 non-repetitive strains were isolated from burn patients from different samples.
Background: Pseudomonas aeruginosa is a known opportunistic pathogen frequently causing serious infections in burned patients.
Aim: To analyze the epidemiological profile of Pseudomonas aeruginosa isolated in a Tunisian burn unit.
Methods: During a 3-year period (from 01 July 2008 to 30 June 2011), 544 non repetitive strains of P.
Background: Pseudomonas aeruginosa is a known opportunistic pathogen frequently causing serious infections in burned patients.
Aim: To analyze the epidemiological profile of Pseudomonas aeruginosa isolated in a Tunisian burn unit.
Methods: During a 3-year period (from 01 July 2008 to 30 June 2011), 544 non repetitive strains of P.
Background: Urinary infection is a frequent pathology in the community as well as at the hospital.
Aim: To analyze the profile of bacteria isolated from urinary tract infectious in women and their antimicrobial resistance.
Methods: During two year period (1 January 2005 to 31 December 2006), 4536 urinary specimens were analyzed at the Laboratory of Aziza Othmana Hospital.
Background: Fluoroquinolones (FQ) use has been identified as a risk factor for colonization and infection to methicillin resistant Staphylococcus aureus(MRSA), Pseudomonas aeruginosae multiresistant(PMR), Acinetobacter multiresistant (AMR) and multidrug resistant bacteria(MDRB).
Aim: Our study proposes to measure the annual antibiotic use of FQ and antimicrobial resistance in P. aeruginosa, S.
Background: Fluoroquinolones (FQ) use has been identified as a risk factor for colonization and infection to methicillin resistant Staphylococcus aureus(MRSA), Pseudomonas aeruginosae multiresistant(PMR) , Acinetobacter multiresistant (AMR) and multidrug resistant bacteria(MDRB).
Aim: Our study proposes to measure the annual antibiotic use of FQ and antimicrobial resistance in P. aeruginosa, S.
Background: The increasing consumption of antibiotics in hospitals and the economic implications of this increase lead to survey this consumption in the various hospital units.
Aim: Our study proposes to measure the annual antibiotic use and antimicrobial resistance in an intensive care Burn department in order to manage the control measures.
Methods: The study was conducted during a 5 year period (1 January 2000 to 31 December 2004).
Background: Nosocomial infections remain the main cause of morbidity and mortality in burn patients. Ongoing surveillance of infections in burned patients is essential to detect changes in epidemiology and to guide better empirical antibiotherapy and infection control policies. The aim of this study is to analyze the bacterial flora and the antibiotic resistance of isolates in a burn department during a two year period
Methods: From 1 January 2005 to 31 December 2006, 1268 strains were isolated from different specimens.
Background: Controlling antibiotic resistance of bacteria is a priority for public healthcare.
Aim: This study concerned the frequency of multidrug resistant bacteria (MDRB) in a Tunisian Hospital with the aim of establishing guidelines for MDRB prevention.
Methods: The study was conducted during two years (1 January 2005-31 December 2006).
Background: The increasing consumption of antibiotics in hospitals and the economic implications of this increase lead to survey this consumption in the various hospital units.
Aim: Our study proposes to measure the annual antibiotic use and antimicrobial resistance in an intensive care Burn department in order to manage the control measures.
Methods: The study was conducted during a 5 year period (1 January 2000 to 31 December 2004).
This study aimed to evaluate the relationship between antimicrobial resistance in Pseudomonas aeruginosa and annual antibiotic use in a burn unit. From 1 January 2000 to 31 December 2004, 203 non-repetitive strains of Ps. aeruginosa were recovered from various clinical specimens.
View Article and Find Full Text PDFMethicillin resistant Staphylococcus aureus (MRSA) constitutes one of the main causes of nosocomial infections in badly burnt patients. The purpose of our study was to determine the frequency and evolution of Methicillin resistant Staphylococcus strains in the department of resuscitation of badly burnt patients of Hopital AZIZA OTHMANA. From January 1, 2000 to December 31, 2003, tests for Staphylococcus aureus proved positive in 139 patients on at least, one occasion.
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