Publications by Amelia M Pearson

Publications by authors named "Amelia M Pearson"

Front Physiol

January 2022

* Mice are useful for research due to their genetic similarity to humans, but their biology presents challenges for accurately simulating endometriosis, as they do not menstruate and have a different reproductive anatomy.
* Recent advancements in murine models have introduced techniques like fluorescence imaging and novel hormonal treatments, enhancing the quality of research and moving towards better models for understanding and treating endometriosis.

- Amelia M Pearson's recent research focuses on the challenges and progress in developing an optimal murine model for studying endometriosis, a common gynecological disorder linked to pelvic pain and infertility
- The study emphasizes the complexities of using mice as a model for endometriosis due to their unique physiological characteristics, such as not having a menstrual cycle and a closed tubo-ovarian junction
- Pearson's work contributes to the understanding of disease modeling in preclinical research, highlighting the need for improved methods to study the pathophysiology of endometriosis and inform therapeutic strategies