Publications by authors named "Amelia Goff"

Hospitals are risk environments for people who use drugs, and most hospitals are unprepared to deliver substance use disorder (SUD) care, including harm reduction (HR) interventions. HR philosophy clashes with traditional hospital hierarchy and norms, and staff may resist HR interventions due to stigma, fear of enabling substance use, legal and safety concerns. Nurses are central to hospital culture and care and could promote and deliver HR care.

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Article Synopsis
  • Low-dose buprenorphine initiation allows patients with opioid use disorder (OUD) to transition from full-agonist opioids while managing acute pain during hospitalization.
  • A study evaluated the rapid low-dose initiation protocol in hospitalized patients, finding that 79% completed the protocol within an average of 72 hours without any cases of precipitated withdrawal.
  • This approach demonstrates that rapid initiation of buprenorphine is a viable and well-received option for patients needing treatment during short or unpredictable hospital stays.
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Background: Illicitly manufactured fentanyl (IMF) is increasing in international drug supply chains, and IMF-related opioid overdose deaths are rising in North America. Hospitalizations among patients with opioid use disorder (OUD) are also rising; and, hospitalized patients are at increased risk of overdose and death following hospital discharge. Hospitalization is a key opportunity to engage patients with OUD.

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