Publications by authors named "Amele Fifi Chantal Kouevi"
Article Synopsis
- Asymptomatic carriers of Plasmodium falciparum play a crucial role in malaria transmission, prompting a study to assess malaria infection levels among household members of children receiving seasonal malaria chemoprevention (SMC).
- The study, which involved 745 participants and used various diagnostic tests, found that 26.58% of participants carried asexual forms of the parasite, with the highest prevalence (35.76%) among children aged 5 to 15 years.
- The ultrasensitive rapid diagnostic test (usRDT) showed greater sensitivity for detecting malaria compared to the standard rapid diagnostic test (rRDT), suggesting that usRDT is more effective for community-based screening and treatment strategies.
Background: Seasonal malaria chemoprevention (SMC) is an effective malaria preventive intervention in sub-Sahara Africa. However, as with any other drug-based intervention, the large-scale deployment of this strategy could lead to Amodiaquine plus Sulfadoxine-Pyrimethamine (AQSP) drug pressure on the circulating parasites population with selection for specific alleles that could compromise the impact of the intervention in the near future. This study aimed to assess the distribution of the Pfmdr1 mutation involved in resistance to AQ before and after the annual campaign of SMC in the health district of Nanoro.
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