Publications by authors named "Amel Maaroufi"

Introduction: patient education is a key component of positive pregnancy and childbearing experiences, especially in women with gestational diabetes (GDM). Scant studies assessed the impact of tailored self-care education on pregnancy outcomes in pregnant women with gestational diabetes mellitus (GDM). This study aimed to assess the effect of a tailored-care education programme on maternal and neonatal outcomes in pregnant women with GDM during pregnancy and at birth.

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Xeroderma pigmentosum (XP) is a rare genodermatosis predisposing to skin cancers. Autoimmune diseases related to XP are rarely discussed in the literature. Type 1 diabetes (T1D) has been associated with other genodermatoses like Cockayne syndrome, but it has never been described in XP.

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Coronavirus disease 2019 (COVID-19) was first reported in December 2019. The disease is caused by severe acute respiratory syndrome virus corona virus 2 (SARS-CoV-2). Mild respiratory symptoms are the most common manifestations of SARS-CoV-2, but new signs are constantly being discovered as it spreads.

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Acromegaly is, in most cases, caused by growth hormone secreting pituitary adenomas. Those patients often develop different pathologies of the thyroid gland, however, the occurrence of Grave´s disease is quite a rare situation. We report a case of a 64-year-old female patient who presented with signs of hyperthyroidism and imbalance of her diabetes mellitus.

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Background: Although it takes more time, the Glucagon Stimulation Test (GST) is a reliable measure for assessing growth hormone (GH) and Adrenocorticotropic Hormone (ACTH) secretion. The GST is considered to be a safe test; however, it still has mild side effects and potential risks.

Objectives: The objective of this study was to analyze the side effects of the GST while testing adrenal-insufficient patients.

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Aims And Methods: Prolactinomas are a common cause of sexual dysfunction and infertility. We aimed, through this case report, to illustrate the difficulties of management of women with giant prolactinoma, especially in cases of desire of pregnancy.

Results: A 30-year-old woman was referred to our department for secondary amenorrhea.

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Context: Diabetic foot trophic disorders and their complications leading to the risk of amputation remain a major public health problem.

Objective: To determine the level of podiatric risk in our diabetic patients according to the classification of the International Working Group of the Diabetic Foot (IWGDF) and study the relationship between the level of education and the level of podiatry risk..

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The presence of prostatic tissue, in addition to uterus and adrenal tumors, is possible in 46XX patients with CAH. Lesions of these organs are usually benign. However, complications including prostate and adrenal cancer were also reported.

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Congenital adrenal hyperplasia refers to a group of rare genetic disorders affecting the adrenal glands. 21-hydroxylase deficiency is the most prevalent and the most studied cause while the remaining enzymatic defects are less common, accounting for less than 10% of cases. We herein described the clinical, biological and molecular characteristics and outcome of patients of the same family diagnosed with 11-Beta-hydroxylase deficiency.

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Article Synopsis
  • Shift work can lead to significant health issues, specifically an increased risk of metabolic syndrome (MS), impacting workers globally.
  • A study in Tunisia with 263 male electricity production workers showed that of those who worked shifts, 51.2% were diagnosed with MS, compared to only 27.2% of non-shift workers, indicating a strong association between shift work and MS.
  • The findings suggest the need for preventive measures, including improved working conditions, dietary changes, and regular exercise, to mitigate these health risks for shift workers.*
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  • Ketosis-prone diabetes is a serious complication arising from ketone build-up in the blood, particularly noted in Tunisia, where there's limited data about its prevalence and characteristics.
  • This study analyzed 391 patients with inaugural ketosis over a 6-year period, categorizing them into two groups based on the presence of autoimmune factors (DAI and DNAI).
  • Findings revealed that young adult males are predominantly affected, with viral infections being the most significant contributing factor to ketosis onset, especially in those with autoimmune features.
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The influence of stress as a precipitating factor associated with the onset of type 1 diabetes have been widely studied in the literature. The relationship between physical and psychological traumas and diabetes has been rarely studied in the military environment. Posttraumatic diabetes is a controversial topic.

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Studies evaluating the metabolic profiles of ENSs are scarce and presented controversial conclusions. This study aimed to compare the metabolic profiles of ENSs' and AHNSs' groups. Males aged 25-45 years and free from a known history of metabolic and/or cardiovascular diseases were included.

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Article Synopsis
  • About 30% of children with idiopathic growth hormone deficiency (IGHD) have other hormone deficiencies, particularly impacting cortisol levels during stress.
  • The study tested 39 children with IGHD using the glucagon stimulation test (GST) to check for adrenal insufficiency, finding that 25.64% had low cortisol response.
  • Children with both growth hormone and ACTH deficiencies had significantly lower peak growth hormone levels than those with IGHD alone, indicating a need for monitoring as many may lack obvious symptoms of adrenal insufficiency.
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Vasculitis is a rare complication of antithyroid drugs (ATDs). It was first described with Propylthiouracil (PTU). We report a new case of antineutrophil cytoplasmic antibody (ANCA) vasculitis with glomerulonephritis induced by Benzylthiouracile (BTU).

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The antiphospholopid syndrome has been associated with thromboembolic events, thrombocytopenia and fetal loss. Some patients with the antiphospholipid syndrome may develop an acutely catastrophic syndrome characterized by multiple vascular occlusions which often results in death. Most patients dye as a result of a combination of cardiac and pulmonary failure.

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