Publications by authors named "Amel Hadj Ziane-Zafour"
Although niflumic acid (NA) is one of the most used non-steroidal anti-inflammatory drugs, it suffers from poor solubility, low bioavailability, and significant adverse effects. To address these limitations, the complexation of NA with cyclodextrins (CDs) is a promising strategy. However, complexing CDs with low molecular weight drugs like NA can lead to low CE.
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- The study focuses on creating new nanocurcumin-based products to combat oxidative stress and diabetes.
- Nanocurcumin is encapsulated in biopolymers from corn starch and fenugreek, achieving high encapsulation rates and demonstrating improved stability and dissolution rates.
- Both formulations showed strong antioxidant activity and significantly lowered blood sugar levels in diabetic rats, supporting their potential as therapeutic options.
The aim of this work was to stabilize oil-in-water nanoemulsion containing sage (salvia officinalis) essential oil, for enhancing its physicochemical stability and enlarging its industrial applications. New β-cyclodextrin nanosponges were synthesized by polycondensation using naphthalene dicarboxylic acid as cross-linking agent, the latter system was characterized by FTIR spectroscopy, SEM, BET, and powder XRD. Nanoemulsions stabilized by free β-cyclodextrin or nanosponges were prepared, their physicochemical properties were determined (particles size, zeta potential, viscosity, turbidity, and essential oil content) and their stability was studied at different storage temperatures (4 °C, 20 °C, and 40 °C) during 3 months.
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