New insights into the antibacterial mode of action of quercetin against uropathogen Serratia marcescens in-vivo and in-vitro.

In the course of a quest for therapeutic agents inhibiting uropathogens, the rise and universal blowout of antibiotic-resistant organisms is a wide problem. To overcome this matter, exploration of alternative antimicrobials is necessary. The antimicrobial potential of quercetin has been widely described against some pathogenic microorganisms, but to the best of our knowledge, no report exists against the pathogenicity of uropathogenic Serratia marcescens.

COVID-19 and police personnel: An exploratory community based study from South India.

Introduction: COVID-19 has ensured that countries enforced complete lock down to prevent the spread of infection. Despite millions of people working from home during this pandemic situation, police personnel 'the front line workers' who deal with the general population to ensure their safety and wellbeing are at risk of stress and other mental health problems in addition to the risk of infection itself.

Aim: The aim of this study is to explore the perception of police personnel towards the disease, factors influencing stress and coping abilities of them amid COVID-19.

Structured form of DHA prevents neurodegenerative disorders: A better insight into the pathophysiology and the mechanism of DHA transport to the brain.

Docosahexaenoic acid (DHA) is one of the most important fatty acids that plays a critical role in maintaining proper brain function and cognitive development. Deficiency of DHA leads to several neurodegenerative disorders and, therefore, dietary supplementations of these fatty acids are essential to maintain cognitive health. However, the complete picture of how DHA is incorporated into the brain is yet to be explored.

Listeria monocytogens - Amended understanding of its pathogenesis with a complete picture of its membrane vesicles, quorum sensing, biofilm and invasion.

Listeria monocytogenes is a ubiquitous, intracellular foodborne pathogen that causes listeriosis in animals and humans. Pathogenic Listeria monocytogenes easily adapted to the conditions of human gastrointestinal tract and tolerate the counter changes such as acidity, bile, osmolarity, and antimicrobial peptides. They secrete specialized biologically active extra organ called membrane vesicles which comprises proteins, lipids, and lipopolysaccharides.