Publications by authors named "Ambrosini F"
Introduction: Benign prostatic hyperplasia (BPH) is a common urological disease that is strongly associated with the aging process and can lead to lower urinary tract symptoms (LUTS). LUTS due to BPH can significantly affect the quality of life of many patients. Among the treatments available for BPH to improve symptoms and functional outcomes, drug therapy and surgical therapy are the options of choice.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to evaluate the surgical and cancer-related results of salvage radical prostatectomy (sRP) after treatment failure in patients who initially received primary therapy.
- Researchers analyzed data from patients who underwent either primary or salvage surgery, comparing outcomes like recurrence-free survival, surgical complications, and recovery times.
- Findings indicated that sRP performed by experienced surgeons yielded similar outcomes in terms of cancer control and recovery compared to primary radical prostatectomy, though the study's retrospective design was a notable limitation.
Background: Measuring psychological constructs in children presents unique challenges, as careful consideration of children's cognitive and socioemotional development is needed. The Trait Emotional Intelligence Questionnaire-Child Form (TEIQue-CF) was developed within the theoretical underpinnings of trait Emotional Intelligence theory and is predicated on primary aged children. This review aims to systematize the scientific literature on the TEIQue-CF, its corresponding short form, the TEIQue-CSF and the translated versions of these tools to identify the key outcomes predicted by these forms in children aged 8-13 years.
View Article and Find Full Text PDFBackground: To explore the detection rates of clinically significant prostate cancer (csPCa; ISUP ≥2) in patients with a single MRI lesion that is visible or invisible on transrectal ultrasound (TRUS) during biopsy.
Methods: Retrospective analyses of patients who underwent targeted and systematic biopsy of the prostate for one MRI-visible lesion (PI-RADS score ≥ 3) between 2017 and 2022. TRUS-visibility, PI-RADS score, and clinical parameters were recorded prospectively.
Objectives: To evaluate the long-term oncological outcomes and functional results of the neurovascular structure-adjacent frozen-section examination (NeuroSAFE) during nerve-sparing (NS) radical prostatectomy (RP).
Materials And Methods: A 10-yr survival analysis on 11069 RPs performed with or without the NeuroSAFE, between January 2002 to June 2011 was carried out. In the NeuroSAFE cohort, the neurovascular structure-adjacent prostatic margins are removed and stained for cryo-sectioning during RP.
The aim of this study is to evaluate the possible benefits of using video consent in the preoperative ureteroscopy (URS) consent process. Prospective randomized trials took place at two Italian tertiary-care centers from March 2022 to September 2022. Patients were randomly assigned to two groups: Group A (standard verbal/written informed consent) and Group B (informed consent supported by video).
View Article and Find Full Text PDFBackground: In a subset of patients with oligorecurrent prostate cancer (PCa), salvage surgery with prostate-specific membrane antigen (PSMA) radioguided surgery (PSMA-RGS) seems to be of value.
Objective: To evaluate whether a lower level of postoperative prostate-specific antigen (PSA; <0.1 ng/ml) is predictive of therapy-free survival (TFS) following salvage PSMA-RGS.
Introduction: We evaluated the prognostic role of pre-salvage prostate-specific membrane antigen-radioguided surgery (PSMA-RGS) serum levels of alkaline phosphatase (AP), carcinoembryonic antigen (CEA), lactate dehydrogenase (LDH), and neuron-specific enolase (NSE).
Materials And Methods: Patients who consecutively underwent PSMA-RGS for prostate cancer (PCa) oligorecurrence between January 2019 and January 2022 were selected. Biomarkers were assessed one day before surgery.
Background: To date, the benefit of image guidance during robot-assisted surgery (IGS) is an object of debate. The current study aims to address the quality of the contemporary body of literature concerning IGS in robotic surgery throughout different surgical specialties.
Methods: A systematic review of all English-language articles on IGS, from January 2013 to March 2023, was conducted using PubMed, Cochrane library's Central, EMBASE, MEDLINE, and Scopus databases.
Objective: In contrast to other malignancies, histologic confirmation prior treatment in patients with a high suspicion of clinically significant prostate cancer (csPCA) is common. To analyze the impact of extracapsular extension (ECE), cT-stage defined by digital rectal examination (DRE), and PSA-density (PSA-D) on detection of csPCA in patients with at least one PI-RADS 5 lesion (hereinafter, "PI-RADS 5 patients").
Materials And Methods: PI-RADS 5 patients who underwent MRI/Ultrasound fusion biopsy (Bx) between 2016 and 2020 were identified in our institutional database.
Article Synopsis
- Bladder cancer ranks as one of the most common cancers, being the 7th most prevalent in males and the 17th in females.
- The incidence and death rates from bladder cancer vary widely across different countries, influenced by various risk factors and healthcare quality.
- Early diagnosis and treatment options significantly affect the outcomes and recurrence rates of this type of cancer.
Purpose: To compare oncological, functional, and surgical outcomes of a large cohort of patients who underwent open retropubic radical prostatectomy (ORP) or robot-assisted radical prostatectomy (RARP).
Materials And Methods: Data from 18,805 RPs performed with either the open or the robot-assisted approaches at a single tertiary referral center between 2008 and 2022 were analyzed. The impact of surgical approach on biochemical recurrence-free survival, salvage radiotherapy-free survival, and metastasis-free survival was analyzed by log-rank test and Kaplan-Meier analysis in a propensity score (PS)-based matched cohort.
Cite this article as: Mantica G, Ambrosini F, Malinaric R, Calarco A, Terrone C. Risk related to increasing indications for retrograde intrarenal surgery (RIRS). Urol Res Pract.
View Article and Find Full Text PDFObjectives: To evaluate the advantages of adding acupuncture to standard postoperative pain management for open radical prostatectomy (RP).
Materials And Methods: A randomized controlled trial (1:1:1) comparing routine postoperative analgesic care (control [CON]) vs the addition of press tack needle acupuncture (ACU) or press tack placebo acupressure (SHAM) for pain management after open RP was performed. A total of 126 patients were enrolled between February 2020 and April 2021.
: While systematic reviews highlight the advantages of laparoscopic nephrectomy over traditional open surgery, the impact of an assistant's experience on surgical outcomes remains unclear. This study aims to evaluate whether the level of assistant expertise influences laparoscopic nephrectomy outcomes. : Retrospective data from our institutional database were analyzed for patients who underwent laparoscopic nephrectomy between January 2018 and December 2022.
View Article and Find Full Text PDFPropofol is used for anesthetic induction in cats and procedural sedation in countries where alfaxalone is not available. Studies have reported propofol-related effects in echocardiography variables in dogs and humans. However, there is a lack of echocardiography studies investigating propofol-related effects on cats.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to establish an effective surgical approach for salvage lymph node dissection (SLND) in prostate cancer patients with lymph node recurrence, focusing on the risk of overlooking contralateral nodal involvement.* -
- Researchers analyzed data from 60 patients who underwent PSMA-radioguided SLND, comparing pre-surgery PSMA-PET images to final pathology results, revealing that 23% had bilateral lymph node positivity despite initially unilateral findings.* -
- The findings suggest that while unilateral SLND may be adequate for some patients, there is a significant risk of missing bilateral disease, indicating a need for larger studies to validate these results.*
Article Synopsis
- - Recent alternatives to TURP and laser techniques for Benign Prostatic Hyperplasia (BPH) are being explored, focusing on preserving sexual function and ejaculation.
- - While TURP and traditional laser techniques are effective for BPH and Lower Urinary Tract Symptoms (LUTS), they often compromise ejaculation.
- - New methods like Rezum, AquaBeam, and Urolift show promise, but they lack long-term data on effectiveness, complications, and patient selection.
We present the case of a patient who underwent an open radical prostatectomy with pelvic lymph node dissection (Gleason 4+3, pT3a pN1 R0) in March 2017. In November 2020, prostate-specific membrane antigen (PSMA)-radioguided salvage lymph node dissection was planned due to a single left para-rectal lymph node at a [Ga] Ga-PSMA-I&T PET. In January 2022, the [Ga] Ga-PSMA-I&T PET showed an isolated liver lesion.
View Article and Find Full Text PDFAffective Dependence (AD) is a problematic model of the love relationship that is becoming increasingly prevalent and evident in the context of couple relationships. Similarly, the phenomenon is being observed with growing frequency in daily clinical practice, making it increasingly necessary to identify treatment guidelines that can help clinicians in dealing with AD, while waiting for the literature to reach a consensus on its definition and nosographic profile. The main objective of this work is to explore the existing evidence of effectiveness regarding feasible treatments for Affective Dependence through a scoping review of the international literature carried out using the main scientific databases and following the PRISMA-ScR (PRISMA Extension for Scoping Reviews) guidelines.
View Article and Find Full Text PDFObjective: To assess the influence of biochemical recurrence (BCR) risk groups and PSA kinetics on the outcomes of radioguided surgery against prostate-specific membrane antigen (PSMA-RGS). Currently, neither BCR risk group nor PSA doubling time (PSA-DT), or PSA velocity (PSA-V) are actively assigned or relevant for counseling prior to PSMA-RGS.
Methods: We retrospectively analyzed PSMA-RGS cases for oligorecurrent prostate cancer between 2014 and 2023.
Purpose: To compare the oncological and surgical outcomes of patients with recurrent prostate cancer (PCa) who underwent either open or newly established robot-assisted salvage prostate-specific membrane antigen-radioguided surgery (PSMA-RGS).
Materials And Methods: Patients who consecutively underwent PSMA-RGS for PCa recurrence between January 2021 and December 2022 were identified. The rate of complete biochemical response, biochemical recurrence-free survival [BFS], and the rate of salvage therapy were evaluated.
Purpose: To identify reasons for negative histopathology of specimens from prostate-specific membrane antigen (PSMA) radioguided surgery (PSMA-RGS) in recurrent prostate cancer (PCa) after prostatectomy.
Methods: Of 302 patients who underwent PSMA-RGS, 17 (5.6%) demonstrated a negative histopathology.