Publications by authors named "Ambrose Ashwin Melvin"
Polymer actuators are promising, as they are widely used in various fields, such as sensors and soft robotics, for their unique properties, such as their ability to form high-quality films, sensitivity, and flexibility. In recent years, advances in structural and fabrication processes have significantly improved the reliability of polymer sensing-based actuators. Polymer actuators have attracted considerable attention for use in artificial or biohybrid systems, as they have the potential to operate under diverse conditions with high durability.
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- - Biohybrid robots are being developed for various applications but currently lack a central nervous system, limiting their use in neurodegenerative disease research.
- - A new biohybrid robot-on-a-chip model has been introduced that integrates a brain organoid, motor neuron spheroids, and muscle bundles to assess drug impacts on neurodegenerative diseases for the first time.
- - The model effectively measures the effect of levodopa on muscle movement, showing significant improvements in activity in a Parkinson's disease model, suggesting its potential as a standard for drug evaluation.
Rational design and shaping of soft smart materials offer potential applications that cannot be addressed with rigid systems. In particular, electroresponsive elastic materials are well-suited for developing original active devices, such as pumps and actuators. However, applying the electric stimulus requires usually a physical connection between the active part and a power supply.
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