Publications by authors named "Ambreen Huma"
Article Synopsis
- A reliable RP-HPLC method with UV detection was developed for the accurate measurement of Voriconazole in pure and gel formulations, using a 50:50 acetonitrile-water mobile phase and a flow rate of 1.0 ml/min.
- The method demonstrated excellent linearity (correlation coefficient = 0.9999) and precision, with a percentage relative standard deviation (RSD) of less than 2.0.
- Robustness was evaluated using variables like flow rate and pH; while flow rate significantly affected drug concentration, the method remained straightforward and suitable for daily quality control with a retention time of under 4 minutes.
Casuarina equisetifolia L. is an important medicinal plant widely used to treat various diseases particularly ulcers, diabetes, cough, diarrhea and many infectious and skin diseases. The aim of this research study was to examine the killing mechanism and killing kinetics assay of methanolic bark extract of C.
View Article and Find Full Text PDFSpectrophotometric technique is considered to be the simplest and operator friendly among other available analytical methods for pharmaceutical analysis. The objective of the study was to develop a precise, accurate and rapid UV-spectrophotometric method for the estimation of chlorpheniramine maleate (CPM) in pure and solid pharmaceutical formulation. Drug absorption was measured in various solvent systems including 0.
View Article and Find Full Text PDFThis study assessed the prescribing pattern of irrational use of antibiotic among children under age of 12 years in public and private sector hospitals in Pakistan. The prospective clinical evaluation of drug utilization pattern of antimicrobials from Patient Bedside File (PBF) of in-patients and Culture Sensitivity Test (CST) reports were evaluated to determine the antibiotic resistance. Two indicators recorded to assess antibiotic prescribing were; dose of prescribed antibiotic (low-dose, rational and high -dose) and Indication (valid or invalid).
View Article and Find Full Text PDFMany herbomineral preparations in traditional medicines are being used from time immemorial like Kushta Abrak Safaid, Busoor-e-Labinyah etc. as therapeutics remedies in common ailments such type of preparations are known to have additive and pronounced effects to cure any obstinate disease condition. The main objective of this research study is the formulation of herbomineral capsule (ALG-06) to treat such type of condition like hypopigmentation in case of vitiligo.
View Article and Find Full Text PDFArticle Synopsis
- The study examined the effects of Hibiscus schizopetalus extracts on blood sugar and fat levels in alloxan-induced diabetic rats.
- Both the flower and leaf extracts demonstrated significant reductions in blood glucose levels in normal and diabetic rats, outperforming the standard drug Tolbutamide.
- The methanolic extracts contained various compounds (like carbohydrates, alkaloids, and glycosides) that may contribute to their antihyperglycemic and hypolipidemic properties, indicating a need for further research on their active components.