Evaluation of Adhesive Characteristics of and Isolated from Weaned Piglets.

and strains, previously isolated from weaned piglets, were considered for the evaluation of their adhesive characteristics. Lactobacilli were treated with LiCl in order to remove the surface protein layer, and probiotic activity was compared with those of untreated strains. The autoaggregation, co-aggregation to F18+, and adhesive abilities of LiCl-treated and were significantly inhibited ( < 0.

and as Functional Feed Additives to Prevent Diarrhoea in Weaned Piglets.

The effects of and and their combination were assessed in weaned piglets. Three hundred and fifty weaned piglets (Landrace × Large White), balanced in terms of weight and sex, were randomly allotted to four experimental groups (25 pens, 14 piglets/pen). Piglets were fed a basal control diet (CTRL, six pens) and a treatment diet supplemented with 2 × 10 CFU/g of (PLA, 6 pens), 2 × 10 CFU/g (REU, six pens) and the combination of both bacterial strains (1 × 10 CFU/g of combined with 1 × 10 CFU/g of , P+R, 7 pens) for 28 days.

Diagnosis of Primary Ciliary Dyskinesia by a Targeted Next-Generation Sequencing Panel: Molecular and Clinical Findings in Italian Patients.

Primary ciliary dyskinesia (PCD) is a rare genetic disorder that alters mucociliary clearance, with consequent chronic disease of upper and lower airways. Diagnosis of PCD is challenging, and genetic testing is hampered by the high heterogeneity of the disease, because autosomal recessive causative mutations were found in 34 different genes. In this study, we clinically and molecularly characterized a cohort of 51 Italian patients with clinical signs of PCD.