Publications by authors named "Ambra Pastori"

Article Synopsis
  • Highly pathogenic avian influenza (HPAI A(H5N1)) caused high mortality rates among wild and domestic birds in Europe from 2020 to 2023, notably spreading to fur farms in Finland in July 2023.
  • The virus was detected in animals like silver and blue foxes, minks, and raccoon dogs, showing severe health issues and mutations that may help it adapt to mammalian hosts.
  • Close cooperation between animal and human health authorities was necessary to manage the outbreak and to address potential health impacts, as the virus was linked to mass bird die-offs and vulnerable farm biosecurity practices.
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On 13 October 2023, the National Directorate for Livestock Development in Mozambique was notified of a suspected outbreak of avian influenza in commercial layers. Samples were screened by real-time and conventional RT-PCR and were positive for both H7 and N6. Full genome sequences were obtained for three representative samples.

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BackgroundOver a 3-week period in late June/early July 2023, Poland experienced an outbreak caused by highly pathogenic avian influenza (HPAI) A(H5N1) virus in cats.AimThis study aimed to characterise the identified virus and investigate possible sources of infection.MethodsWe performed next generation sequencing and phylogenetic analysis of detected viruses in cats.

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The illegal trade of animals poses several health issues to the global community, among which are the underestimated risk for spillover infection and the potential for an epizootic in both wildlife and domestic naïve populations. We herein describe the genetic and antigenic characterization of viruses of the specie detected at high prevalence in puppies illegally introduced in North Eastern Italy and compared them with those circulating in wild carnivores from the same area. We found evidence of a wide diversity of canine parvoviruses (CPV-2) belonging to different antigenic types in illegally imported pups.

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Hantaviruses include several zoonotic pathogens that cause different syndromes in humans, with mortality rates ranging from 12 to 40%. Most commonly, humans get infected through the inhalation of aerosols or dust particles contaminated with virus-containing rodent excreta. Hantaviruses are specifically associated with the host species, and human cases depend on the presence and the dynamics of reservoir hosts.

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In January 2021, Senegal reported the emergence of highly pathogenic avian influenza virus A(H5N1), which was detected on a poultry farm in Thies, Senegal, and in great white pelicans in the Djoudj National Bird Sanctuary. We report evidence of new transcontinental spread of H5N1 from Europe toward Africa.

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The first detection of a Highly Pathogenic Avian Influenza (HPAI) H5N8 virus in Bulgaria dates back to December 2016. Since then, many outbreaks caused by HPAI H5 viruses from clade 2.3.

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Despite the reported increase in SARS-CoV-2-infected pets, the description of the clinical features from natural infection and the medical follow up in symptomatic pets is still not sufficiently documented. This study reports the case of an indoor cat that displayed respiratory signs and a gastrointestinal syndrome, following the COVID-19 diagnosis of his owners. Thoracic radiographies were suggestive of bronchial pneumonia, while blood tests were indicative of a mild inflammatory process.

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Article Synopsis
  • * A study analyzed 20 highly pathogenic avian influenza H5N8 viruses from live bird markets and reported outbreaks between 2016 and 2019, revealing four distinct genetic groups related to different geographic origins.
  • * The findings underscore the importance of unified surveillance efforts in Nigeria and surrounding regions to manage avian influenza and prevent potential zoonotic transmission to humans.
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: Identify genes associated with ocular sarcoidosis (OS).: We genotyped 1.1 million genetic variants to identify significant OS associations, defined as those that achieved < 5 × 10 in a genome-wide comparison of OS cases to healthy controls in our European- or African-American cohorts (EA, AA).

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