Publications by authors named "Ambra Colombo"
Eur J Med Chem
November 2016
Article Synopsis
- Researchers synthesized and characterized new compounds called 6-substituted pyrazolo[3,4-d]pyrimidines and pyrazolo[4,3-e][1,2,4]triazolo[4,3-a]pyrimidines.
- These compounds were tested for their effectiveness against Abl and Src kinases in vitro.
- Compounds 7a and 7b showed the strongest activity against both wild and mutant Abl kinases, as well as the Src kinase and the leukemia K-562 cell line, indicating potential for further development.
