In the field of pharmaceutical supply chains, there is a lack of comprehensive historical data, representing a significant barrier to advancing research. To address this gap, we introduce a high-resolution dataset comprising drug packages distributed to approximately 300,000 pharmacies, hospitals, and practitioners across the US. We reconstruct 375 million distribution paths from ARCOS, a DEA-maintained database comprising half a billion shipping records between 2006 and 2014.
View Article and Find Full Text PDFSupply chain disruptions may cause shortages of essential goods, affecting millions of individuals. We propose a perspective to address this problem via reroute flexibility. This is the ability to substitute and reroute products along existing pathways, hence without requiring the creation of new connections.
View Article and Find Full Text PDFThe perception of facial attractiveness is a complex phenomenon which depends on how the observer perceives not only individual facial features, but also their mutual influence and interplay. In the machine learning community, this problem is typically tackled as a problem of regression of the subject-averaged rating assigned to natural faces. However, it has been conjectured that this approach does not capture the complexity of the phenomenon.
View Article and Find Full Text PDFThe origin and meaning of facial beauty represent a longstanding puzzle. Despite the profuse literature devoted to facial attractiveness, its very nature, its determinants and the nature of inter-person differences remain controversial issues. Here we tackle such questions proposing a novel experimental approach in which human subjects, instead of rating natural faces, are allowed to efficiently explore the face-space and "sculpt" their favorite variation of a reference facial image.
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