Publications by authors named "Ambily Vasudevan"
BMC Med Genet
January 2017
Article Synopsis
- Mutations in the WT1 gene are commonly studied in children with steroid-resistant nephrotic syndrome (SRNS), and this study aimed to screen for such mutations.
- A standardized High Resolution Melt (HRM) assay was developed to quickly and cost-effectively identify potential mutations before further sequencing.
- The study found no WT1 mutations in the 100 SRNS patients tested, suggesting low prevalence, and recommends using HRM as the initial screening tool in clinical settings.
