Publications by authors named "Ambika S"

In this work, we report TiCT MXene bonded cationic perylene diimide (PDI) as a redox charge storage host for seawater-based electrolytes. A reversible and stable charge storage capacity of ∼101 mA h g is achieved in 3 M MgCl electrolytes at a current density of 0.25 A g with an extended cycling stability of more than 8000 cycles.

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Purpose: To measure the reading eye movement's parameters and quantify the oculomotor dysfunction among subjects with homonymous hemianopia compared to age-matched controls using ReadAlyzer.

Methods: This was a prospective study carried out in the neuro-optometry clinic of a tertiary eye care hospital in South India, from October 2018 to Janurary 2019. Fifty consecutive patients diagnosed with homonymous hemianopia were enrolled in the study after obtaining their written informed consent.

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Optic neuropathy can be of infectious or non-infectious/idiopathic aetiology. Many infectious organisms can cause optic neuropathy that can be of varied presentation including papillitis, retrobulbar optic neuritis, neuroretinitis, and optic perineuritis. Detailed history, ocular, systemic/neurologic examination along with appropriate laboratory evaluation can help clinicians to identify the infectious agent causing optic neuropathy.

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For environmental sustainability and to achieve sustainable development goals (SDGs), drinking water treatment must be done at a reasonable cost with minimal environmental impact. Therefore, treating contaminated drinking water requires materials and approaches that are inexpensive, produced locally, and effortlessly. Hence, locally available materials and their derivatives, such as biochar (BC) and activated carbon (AC) were investigated thoroughly.

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Purpose: To study the optic nerve head characteristics on optical coherence tomography (OCT) in patients with papilledema and correlate them with intracranial pressure (ICP).

Methods: A retrospective hospital-based study of 46 eyes of 23 patients with bilateral optic disc edema secondary to increased ICP. The clinical profile and the OCT features in terms of retinal nerve fiber layer thickness (RNFL), ganglion cell inner plexiform layer (GCIPL) thickness, and enhanced depth imaging (EDI) B scan images of the optic nerve head were studied and correlated with the ICP.

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Purpose: To measure the pupillary dynamics and accommodative response in individuals with mild traumatic brain injury (mTBI) as compared to age-matched controls.

Materials And Methods: This prospective comparative study was carried out at the neuro-optometry clinic of a tertiary eye care hospital. Sixty-three subjects with a history of mTBI and ninety age-matched controls were enrolled in this study.

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Tanning and other leather processing methods utilize a large amount of freshwater, dyes, chemicals, and salts and produce toxic waste, raising questions regarding their environmental sensitivity and eco-friendly nature. Total suspended solids, total dissolved solids, chemical oxygen demand, and ions such as chromium, sulfate, and chloride turn tannery wastewater exceedingly toxic for any living species. Therefore, it is imperative to treat tannery effluent, and existing plants must be examined and upgraded to keep up with recent technological developments.

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Presently, owing to the rapid development of industrialization and urbanization activities, a huge quantity of wastewater is generated that contain toxic chemical and heavy metals, imposing higher environmental jeopardies and affecting the life of living well-being and the economy of the counties, if not treated appropriately. Subsequently, the advancement in sustainable cost-effective wastewater treatment technology has attracted more attention from policymakers, legislators, and scientific communities. Therefore, the current review intends to highlight the recent development and applications of biochars and/or green nanoparticles (NPs) produced from agricultural waste via green routes in removing the refractory pollutants from water and wastewater.

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Purpose: Ethambutol (EMB) is one of the first-line drugs used for treating tuberculosis. Vision loss due to optic nerve toxicity is a well-known potential side effect of the drug. Our aim was to evaluate the clinical features and visual outcomes of patients with EMB optic neuropathy (EON).

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Purpose: To report the ocular features of patients with PD who presented with visual complaints to a tertiary eye care center.

Methods: This was a retrospective study carried out between January 2015 and March 2020 at the Neuro-Optometry clinic of a tertiary eye care center in Southern India. All PD patients with ocular complaints examined by the neuro- ophthalmologists were referred to Neuro-Optometry Clinic for detailed evaluation.

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This study was aimed to test simultaneous detection of antibodies to myelin oligodendrocyte glycoprotein (MOG)/aquaporin4 AQP4) in serum samples of patients with clinically-diagnosed optic neuritis (ON), by fixed cell-based immunofluorescence assay (CBIFA). The study involved 237 serum samples of patients with ON which were tested for MOG and AQP4 antibodies using fixed CBIFA kit which utilizes AQP4 or MOG protein transfected cells as a substrate. Of 237 serum samples, 22 (9%) were positive for AQP4, 66 (28%) were positive for MOG, and 138 (58%) were negative for both AQP4 and MOG antibodies.

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Purpose: To analyze clinical profile, imaging features, and short-term visual outcomes of optic neuritis patients in Indian population with and without seromarkers for myelin oligodendrocyte glycoprotein (MOG)/neuromyelitis optica (NMO).

Methods: Electronic medical records of 203 optic neuritis patients who presented between June 2018 and December 2019 to the Neuro-ophthalmology services of a tertiary care center in India were retrospectively analyzed.

Results: Of 203 patients, 57 patients (28.

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Cobalt (III) Schiff base complexes are of attraction in the context of their potential application in cancer therapy. The aim of this study has been to find the mechanism of action of cobalt (III) Schiff base complexes 1 and 2, the synthesis and characterization of which have already been reported, in inhibiting growth of human breast cancer cell MCF-7 and lung cancer cell A549. The already proclaimed anti-proliferative effect of the cobalt complexes was ascertained using MTT cytotoxicity assay.

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A 13-year-old female presented with decrease in vision in both eyes with headache and vomiting for 15 days. Her visual acuity was perception of light with inaccurate projection in the right eye and counting fingers close to face in the left eye. Pupils were nonreactive.

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Coronavirus disease (COVID-19) spread across the globe through the human transmission. The World Health Organization suggested social distancing to curb the community spread. After national social lockdown started in India, air quality improved drastically.

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A 37-year-old patient presented to our emergency department with sudden onset decreased vision with a history of being treated for COVID 19 3 weeks earlier. On examination, she was found to have a tonic right pupil, which was confirmed with a dilute pilocarpine test. As tonic pupils are known to be caused by neurotropic viruses and our current understanding of the SARS-CoV-2 is that it does affect the nervous system, we feel that the tonic pupil in our patient may be secondary to COVID 19.

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Purpose: To report a rare case of optic neuritis with spine demyelination following H1N1 virus infection.

Observation: A 66-year-old female presented with decreased vision in both eyes (left > right) following a recent episode of fever and flu. She was diagnosed as H1N1 infection confirmed by viral antigen analysis of throat swab.

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Objective: With the increasing global prevalence of acquired brain injury (ABI), the burden of visual problems as a sequelae to ABI is on the rise. This study reports the visual profile of patients with ABI seen in Neuro-Optometry Clinic (NOC) at a tertiary eye-care center in Southern India.

Methods: A retrospective study was carried out between January 2014 and December 2015.

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Background: Nonophthalmologist physicians do not confidently perform direct ophthalmoscopy. The use of artificial intelligence to detect papilledema and other optic-disk abnormalities from fundus photographs has not been well studied.

Methods: We trained, validated, and externally tested a deep-learning system to classify optic disks as being normal or having papilledema or other abnormalities from 15,846 retrospectively collected ocular fundus photographs that had been obtained with pharmacologic pupillary dilation and various digital cameras in persons from multiple ethnic populations.

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Novel meso-zero valent iron (mZVI) was investigated for treating complex wastewater containing toxic heavy metal Cr and organic compound phenol. This study is first of its kind illustrating coupled removal in single-step with HO playing a major role as an oxidant and reductant. The mechanism involved was electron transfer from Fe to Cr resulting in Fe which in turn was consumed for phenol oxidation returning as Fe into the system for further Cr reduction.

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Introduction: According to the World Health Organization, more than 300 million people were estimated to suffer from depression in 2017. Many studies have observed that medical personnel have a higher level of depression, but studies among dentists are scarce. Early diagnosis will help in controlling the morbidity and mortality due to depression.

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Background: Gastrointestinal tumors (GISTs) represent the most common mesenchymal tumors of the gastrointestinal tract. There has been limited data on GIST incidence and survival disparities between ethnic groups.

Aims: Assess disparities in incidence and survival among race in the USA in the era of available GIST histologic codes and treatment.

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Background And Objectives: Conflicting evidence indicates that both race and geographic setting may influence the management of malignancies such as gastric adenocarcinoma (GAC).

Methods: We designed a retrospective cohort study utilizing data from the Surveillance, Epidemiology, and End Results program to identify patients with resectable GAC (N = 15 991). Exposures of interest were race and geographic region of diagnosis (West [WE], Midwest [MW], South [SO], or Northeast [NE]).

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Background: Several prognostic factors have been used to guide therapy for colon cancer (CC). However, the relationship between CC laterality (sidedness) and prognosis remains under investigation.

Objectives: To assess the effect of laterality on CC presentation and survival, using a Surveillance, Epidemiology, and End Results (SEER) population-based cohort.

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