Publications by authors named "Ambika Rao"
Article Synopsis
- Neuropathic feet are highly susceptible to infections and amputations, and the Slipping Slipper Sign (SSS) can help identify severe diabetic peripheral neuropathy through a simple questionnaire that non-medical staff can administer.
- In a study with 74 diabetic patients, those with SSS had longer diabetes duration and higher instances of complications like retinopathy and cerebrovascular accidents compared to those without SSS.
- Nerve conduction studies revealed significant differences in nerve function, with patients showing SSS having markedly reduced sensory nerve action potential and thinner nerve diameters, indicating a correlation between SSS and severe neuropathy.
Transforming growth factor-β (TGF-β) may play a role in the pathogenesis of primary open-angle glaucoma (POAG). Elevated levels of TGF-β are found in the aqueous humor and in reactive optic nerve astrocytes in patients with glaucoma. In POAG, aqueous humor outflow resistance at the trabecular meshwork (TM) leads to increased intraocular pressure and retinal ganglion cell death.
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