Evaluation of the Genetic Diversity, Haplotype, and Virulence of f. sp. Field Isolates from Alabama.

The United States is the third largest producer of cotton and the largest exporter of cotton globally. Fusarium wilt, caused by the soilborne fungal pathogen f. sp.

Inventory of the Secondary Metabolite Biosynthetic Potential of Members within the Terminal Clade of the Species Complex.

The species complex (FSSC) constitutes at least 77 phylogenetically distinct species including several agriculturally important and clinically relevant opportunistic pathogens. As with other Fusaria, they have been well documented to produce many secondary metabolites-compounds that are not required for the fungus to grow or develop but may be beneficial to the organism. An analysis of ten genomes from fungi within the terminal clade (clade 3) of the FSSC revealed each genome encoded 35 () to 48 () secondary metabolite biosynthetic gene clusters (BGCs).

Targeted Gene Disruption Via CRISPR/Cas9 Ribonucleoprotein Complexes in Fusarium oxysporum.

Characterization of a gene of interest frequently relies on generation of a mutant as a critical component. Transformation to disrupt a gene has been previously accomplished by several methods in Fusarium oxysporum. Here we provide a detailed method to generate a gene mutation mediated by a CRISPR/Cas9 ribonucleoprotein (RNP) complex.

The Extracellular Superoxide Dismutase Sod5 From Is Localized in Response to External Stimuli and Contributes to Fungal Pathogenicity.

Reactive oxygen species (ROS) produced by hosts serve as a general defense mechanism against various pathogens. At the interaction site between the host and pathogen, host cells rapidly accumulate high concentrations of ROS, called the oxidative burst, that damage and kill the invading microbes. However, successful pathogens usually survive in a high ROS environment and have evolved strategies to overcome these detrimental effects.

The Genome Sequence of Five Genotypes of f. sp. : A Resource for Studies on Fusarium Wilt of Cotton.

f. sp. is an important plant pathogen responsible for vascular wilt disease on cotton.