Publications by authors named "Amber Malik"
Objectives: This pilot randomized controlled study evaluates the feasibility and preliminary efficacy of a 7-week remote intervention combining well-being therapy and sleep hygiene to improve sleep and psychological outcomes among adults reporting poor sleep and distress.
Methods: Thirty-one participants (81% women, 40.2 ± 13.
Article Synopsis
- The study investigates the role of fibroblast growth factor receptor 1 (FGFR1) in breast cancer, particularly its connection to endocrine therapy resistance and progression.
- Researchers analyzed RNA-seq and microarray data from 1,425 breast cancer patients, finding that genes in the SHH pathway are significantly upregulated in FGFR1-positive cases and linked to poor patient outcomes.
- Combining treatments with FGFR1 inhibitor AZD4547 and GLI1 inhibitor GANT61 not only reduced cancer cell proliferation and invasion but also highlighted the interconnected roles of FGFR1 and GLI1 in breast cancer metastasis, suggesting a potential new therapeutic strategy.
Objectives: Considering the therapeutic potential of honey and Nigella sativa (HNS) in coronavirus disease 2019 (COVID-19) patients, the objective of the study is defined to evaluate the prophylactic role of HNS.
Trial Design: The study is a randomized, placebo-controlled, adaptive clinical trial with parallel group design, superiority framework with an allocation ratio of 1:1 among experimental (HNS) and placebo group. An interim analysis will be done when half of the patients have been recruited to evaluate the need to adapt sample size, efficacy, and futility of the trial.
Introduction: Climate factors play an important role in the transmission of viruses, such as influenza viruses, MERS-CoV, and SARS-CoV-1. This study aimed to determine the relationship between changes in temperature, humidity, rainfall, and SARS-CoV-2 contagion. Five ecologically and climatically distinct regions were considered-Karachi, Lahore, Islamabad, Peshawar, and Gilgit-Baltistan.
View Article and Find Full Text PDFObjectives: The objective of the study is to measure the efficacy of ionic-iodine polymer complex [1] for clinical and radiological improvement in coronavirus disease 2019 (COVID-19) patients.
Trial Design: The trial will be closed label, randomized and placebo-controlled with a 1:1:1:1 allocation ratio and superiority framework.
Participants: All PCR confirmed COVID-19 adult patients including non-pregnant females, with mild to moderate disease, will be enrolled from Shaikh Zayed Post-Graduate Medical Complex, Ali Clinic and Doctors Lounge in Lahore (Pakistan).