Publications by authors named "Amber J Trauth"
SARS-CoV-2 mRNA vaccines are administered as effective prophylactic measures for reducing virus transmission rates and disease severity. To enhance the durability of post-vaccination immunity and combat SARS-CoV-2 variants, boosters have been administered to two-dose vaccinees. However, long-term humoral responses following booster vaccination are not well characterized.
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- The COVID-19 pandemic, caused by SARS-CoV-2, significantly affected healthcare, the workforce, and global economies, highlighting the need for effective vaccinations.
- Multi-dose mRNA vaccines, like the Pfizer/BioNTech BNT162b2, have proven effective against SARS-CoV-2 and its variants, with a focus on neutralizing antibodies targeting the virus's receptor-binding domain (RBD).
- A longitudinal study involving nine uninfected individuals showed that two doses of the mRNA vaccine produced strong humoral antibody responses across the entire spike protein, revealing new non-RBD epitopes that could enhance future vaccine and drug development.