Publications by authors named "Amber E Cranston"

Background: To facilitate deployment of point-of-care testing for severe acute respiratory syndrome coronavirus 2, we evaluated the Access Bio CareStart COVID-19 Antigen test in a high-throughput, drive-through, free community testing site using anterior nasal (AN) swab reverse-transcription polymerase chain reaction (RT-PCR) for clinical testing.

Methods: Consenting symptomatic and asymptomatic children (≤18 years) and adults received dual AN swabs. CareStart testing was performed with temperature/humidity monitoring.

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Article Synopsis
  • Rapid diagnostic tests (RDTs) for SARS-CoV-2, like the Abbott BinaxNOW, can enhance COVID-19 testing at point of care by providing quick results alongside traditional molecular tests.
  • A study in Massachusetts evaluated the effectiveness of BinaxNOW by comparing its results with standard PCR tests among both symptomatic and asymptomatic individuals, covering over 2,400 participants.
  • The findings showed high sensitivity (96.5% for adults and 84.6% for children with symptoms) and excellent specificity (100% for both groups), but lower sensitivity for asymptomatic individuals (70.2% for adults and 65.4% for children).
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