Publications by authors named "Amber Dunlop"

Article Synopsis
  • This review examines concerns about the effects of paracetamol on neurodevelopment in preterm infants treated for patent ductus arteriosus (PDA).
  • A thorough search of medical literature found seven studies that evaluated neurodevelopmental outcomes related to paracetamol use in infants born before 32 weeks of gestation.
  • The findings indicate no significant differences in neurodevelopmental outcomes between paracetamol-treated infants and control groups, but more robust studies are needed for conclusive evidence.
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Background And Objectives: Adherence to medical treatment following a kidney transplant is particularly challenging during adolescence and young adulthood. There is increasing evidence of the benefits of the use of computer and mobile technology (labelled as eHealth hereafter) including serious gaming and gamification in many clinical areas. We aimed to conduct a systematic review of such interventions designed to improve self-management skills, treatment adherence and clinical outcomes in young kidney transplant recipients aged 16 to 30 years.

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Article Synopsis
  • National data on colorectal cancer (CRC) stage at diagnosis in the UK is incomplete, as the NHS does not directly collect site-specific fast-track cancer data, which can lead to inaccuracies in policy making.
  • A review of studies from 2000 to 2017 found that only 7.7% of patients referred through the UK's lower gastrointestinal 2-week wait pathway had CRC, with significant proportions diagnosed at advanced stages (Dukes C and D).
  • The results indicate that the 2-week wait pathway may not improve outcomes for CRC diagnosis, as over half of the patients had no colonic pathology, suggesting a need to rethink the effectiveness of this referral system and improve patient selection strategies.
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Background: Colorectal cancer represents the fourth most common cancer in England and Wales; survival is high for early stage disease but declines sharply with advanced stage. UK figures suggest that cancer survival rates are lower than those of other Western European countries. Current 5-year survival is around 50 %.

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