Publications by authors named "Ambalakkuthan Murugesan"
Objectives: To construct reference growth curves for the preterm population from North India and compare it with global charts.
Methods: This prospective study enrolled preterm neonates (23 to 36 weeks) from July 2018 to August 2019 after excluding stillbirths and those with congenital malformations. Anthropometry was performed within 18 hours of birth.
Article Synopsis
- A fetus at 30 weeks gestation with severe complications due to a large vein of Galen malformation (VOGM) was treated with glue embolization after being referred for pregnancy termination.
- The procedure successfully corrected blood flow issues and showed improvements in heart size and fetal brain structure, leading to a stable delivery.
- Despite initial success, the newborn faced severe health challenges and ultimately passed away, highlighting the complexities and risks involved in prenatal interventions for VOGM.
Article Synopsis
- The study aimed to determine the readmission rates of neonates to the NICU after hospital discharge and to describe their clinical characteristics and reasons for readmission.
- A retrospective analysis of data from July 2021 to June 2023 showed that out of 26,403 live births, 5.9% of NICU admissions were readmissions, with common issues being infections, jaundice, and feeding problems.
- The findings revealed that most readmitted neonates (96.4%) were eventually discharged, with a median readmission age of 17 days and a median hospital stay of 5 days.
The objective of this study was to determine the risk factors associated with Elizabethkingia anophelis infection in neonates admitted to a tertiary care neonatal intensive care unit (NICU). A case-control study was undertaken as part of the outbreak investigation for E. anophelis sepsis in a tertiary care NICU in South India.
View Article and Find Full Text PDFObjective: To study the association of fetal growth restriction (FGR) with metabolic bone disease in preterm neonates.
Methodology: This prospective cohort study included 94 preterm neonates with FGR as cases and an equal number of gestation-matched appropriate for gestational age (AGA) neonates without FGR as controls. The incidence of metabolic bone disease, and serum biochemical markers at various time intervals till 6 months corrected age were compared.
Article Synopsis
- Vertical transmission of infections, including scrub typhus, is documented but rare, especially in neonates.
- A notable resurgence of scrub typhus, a tick-borne zoonotic disease, has been observed in tropical regions.
- A specific case is reported where a newborn showed symptoms of scrub typhus within 72 hours of birth, with the causative organism confirmed in both the mother and infant.
Genetic conditions have varied presentations, and one of them is the association with multiple malformation syndrome (MMS), which has a high mortality rate in the immediate postnatal period. Here, we describe a neonate born with multiple anomalies-wide anterior and posterior fontanelle, metopic suture, flat nasal bridge, hypertelorism, low set dysplastic ears, corneal cloudiness, micrognathia, webbed neck, simian crease, undescended testis, hypospadias, congenital talipes equinovarus, hypoplastic inferior cerebellar vermis, poor reflexes, hypotonia and ventricular septal defect. There was a history of sibling death with similar malformations, pointing towards a genetic aetiology.
View Article and Find Full Text PDFExtremely preterm neonates (< 28 wk) are at risk of metabolic complications like hypocalcemia, hypophosphatemia, hyponatremia, and metabolic acidosis. Many of these complications are often the result of prematurity per se, while some of them may be the result of prolonged parenteral nutrition. Most of the complications occur in the initial few weeks of hospital stay, but hyponatremia, hypocalcemia, and hypophosphatemia may persist for longer periods of time.
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