Ventilator-associated events in children: A multicentre prospective cohort study.

Background: The Centres for Disease Control and Prevention (CDC) broadened the focus of surveillance from ventilator-associated pneumonia to ventilator-associated event (VAE) for quality purposes. No paediatric definition of VAE (PaedVAE) has been accurately validated. We aimed to analyse the incidence and impact on patient outcomes resulting from the application of the adult and two paediatric VAE (PaedVAE) criteria.

Quality of life in home-ventilated children and their families.

Unlabelled: HMV (home mechanical ventilation) in children has increased over the last years. The aim of the study was to assess perceived quality of life (QOL) of these children and their families as well as the problems they face in their daily life.We performed a multicentric cross-sectional study using a semi-structured interview about the impact of HMV on families and an evaluation questionnaire about perceived QOL by the patient and their families (pediatric quality of life questionnaire (PedsQL4.

Infection in critically ill pediatric patients on continuous renal replacement therapy.

Introduction: Continuous renal replacement therapies (CRRT) are frequently used in critically ill children and may increase the risk of infection. However, the incidence, characteristics and prognosis of infection in critically ill children on CRRT have not been studied.

Methods: Data from a prospective, single-center register of critically ill children treated with CRRT was analyzed.

Prognostic factors in pediatric sepsis study, from the Spanish Society of Pediatric Intensive Care.

Background: Sepsis and septic shock represent up to 30% of admitted patients in pediatric intensive care units, with a mortality that can exceed 10%. The objective of this study is to determine the prognostic factors for mortality in sepsis.

Methods: Multicenter prospective descriptive study with patients (aged 7 days to 18 years) admitted to the pediatric intensive care units for sepsis, between January 2011 and April 2012.

Nutritional status and clinical outcome of children on continuous renal replacement therapy: a prospective observational study.

Background: No studies on continuous renal replacement therapy (CRRT) have analyzed nutritional status in children. The objective of this study was to assess the association between mortality and nutritional status of children receiving CRRT.

Methods: Prospective observational study to analyze the nutritional status of children receiving CRRT and its association with mortality.

Cardiac output and blood volume parameters using femoral arterial thermodilution.

Background: The pulse-induced continuous cardiac output (PiCCO) system is a less invasive method than pulmonary thermodilution for the measurement of cardiac output and estimating blood volume parameters. The normal values in children have not been defined. The purpose of the present paper was therefore to evaluate cardiac output and parameters of blood volume using femoral arterial thermodilution in critically ill children.

Postpyloric enteral nutrition in the critically ill child with shock: a prospective observational study.

Background: Tolerance to enteral nutrition in the critically ill child with shock has not been studied. The purpose of the study was to analyze the characteristics of enteral nutrition and its tolerance in the critically ill child with shock and to compare this with non-shocked patients.

Methods: A prospective, observational study was performed including critically ill children with shock who received postpyloric enteral nutrition (PEN).

Transpyloric enteral nutrition in the critically ill child with renal failure.

Objective: To study the efficacy and tolerance of transpyloric enteral nutrition (TEN) in the critically ill child with acute renal failure (ARF).

Design: Prospective observational study.

Setting: Paediatric intensive care unit.

Transpyloric enteral feeding in the postoperative of cardiac surgery in children.

Purpose: The aim of this study is to assess the utility of transpyloric enteral nutrition in the postoperative period of cardiac surgery in children.

Methods: A prospective, observational study was performed on children receiving transpyloric enteral nutrition in the postoperative period of cardiac surgery. The type of nutrition, duration, tolerance, and complications were studied.

Severe ischemia of the lower limb and of the intestine associated with systemic vasoconstrictor therapy and femoral arterial catheterization.

Objective: To report a case of peripheral and intestinal ischemia associated with arterial catheterization and terlipressin treatment in a child.

Design: Case report.

Setting: Pediatric intensive care unit of a university hospital.

Prognosis in critically ill children requiring continuous renal replacement therapy.

We performed an observational prospective study in 53 critically ill children to analyze the prognostic factors of children requiring continuous renal replacement therapy. Pediatric index of mortality (PIM), pediatric risk of mortality score (PRISM), multi-organ failure score, serum lactate levels, blood pressure, vasoactive drugs, renal function and characteristics of renal replacement therapy were analyzed. The mortality was 32.

Elevated carboxyhemoglobin associated with sodium nitroprusside treatment.

Objective: To report four cases of carboxyhemoglobinemia associated with high doses of sodium nitroprusside after cardiac transplant in children.

Patients: Four children in the pediatric care unit of a university hospital aged 6 months-4 years. Carboxyhemoglonemia developed at levels of 5.