Publications by authors named "Amarpreet K Thind"
Background: Older people with end-stage kidney disease (ESKD) are vulnerable to frailty, which impacts on clinical and experiential outcomes. With kidney transplantation in older people increasing, a better understanding of patient experiences is necessary for guiding decision making. The Kidney Transplantation in Older People (KTOP):impact of frailty on outcomes study aims to explore this.
View Article and Find Full Text PDFFrailty, characterized by a decreased physiological reserve and an increased vulnerability to stressors, is common among kidney transplant (KT) candidates and recipients. In this review, we present and summarize the key arguments for and against the assessment of frailty as part of KT evaluation. The key arguments for including frailty were: (i) sheer prevalence and far-reaching consequences of frailty on KT, and (ii) the ability to conduct a more holistic and objective evaluation of candidates, removing the inaccuracy associated with 'eye-ball' assessments of transplant fitness.
View Article and Find Full Text PDFSARS-CoV-2 vaccines are recommended pre-transplantation, however, waning immunity and evolving variants mandate booster doses. Currently there no data to inform the optimal timing of booster doses post-transplant, in patients primed pre-transplant. We investigated serial serological samples in 204 transplant recipients who received 2 or 3 SARS-CoV-2 vaccines pre-transplant.
View Article and Find Full Text PDFArticle Synopsis
- The KTOP study investigates the experiences and outcomes of older kidney transplant recipients, focusing on frailty and cognitive impairment affecting their quality of life.
- In this observational study, participants aged 60 and above are assessed for frailty and cognition through various questionnaires and clinical data, which are collected at different stages of the transplantation process.
- Preliminary results show that 36.4% of participants exhibited cognitive impairment while 15.8% were identified as frail, highlighting significant vulnerabilities in this age group.
Article Synopsis
- Pericardial effusions and uremic pericarditis, linked to kidney disease since 1836, have become less common, leading to inconsistent management practices.
- A case study of a 61-year-old woman with a large pericardial effusion before kidney transplantation is presented, alongside a review of 44 similar cases from a renal center over 8 years.
- The study found that pericardial interventions were often necessary due to potential hemodynamic issues, but aspiration had limited diagnostic value, suggesting it should only be used when absolutely necessary.
Background: The rapidly evolving novel coronavirus 2019 (COVID-19) pandemic bought many kidney transplant (KT) programs to a halt. Integral to resuming KT activity is understanding the perspectives of potential transplant candidates during this highly dynamic time.
Methods: From June 1 to July 7, 2020, a telephone survey of KT candidates on the deceased donor waiting list at Imperial College Renal and Transplant Centre in West London was conducted.