Needle in a Haystack: Acute Intermittent Porphyria, an Often-missed Differential Diagnosis of Abdominal Pain.

Acute intermittent porphyria (AIP) is a rare disease that arises due to deficiency of the biosynthetic enzyme porphobilinogen deaminase (PBGD) involved in heme synthesis. Acute attacks can present with abdominal pain and neurological symptoms, although vague in nature. Recurrent hospitalizations for idiopathic intermittent abdominal pain should warrant investigation for AIP.

Porous 3D columnar-sphere of NiO nanomaterials synthesized for supercapacitors hydrothermal route: impact of thiourea concentration.

The charge storage application has witnessed a dramatic increase in terms of the short charge-discharge time of supercapacitors, specifically in highly active electrode materials. For charge storage supercapacitor applications, highly porous materials are preferable. In this research article, thiourea acts as a leaving agent in the preparation of the porous 3D spherical architecture of NiO nanomaterials.

Acute motor axonal neuropathy following SARS-CoV-2 infection in the third trimester of pregnancy.

Neurological complications following SARS-CoV-2 infections are increasingly recognized. Despite that, sequelae from SARS-CoV-2 infection in gravid women are uncommonly reported. We present a case of acute motor axonal neuropathy, a variant of Guillain-Barre syndrome, in a 26-year-old primigravida at 34 weeks' gestation.

Angiotensin II in septic shock.

Septic shock is a life threatening condition and a medical emergency. It is associated with organ dysfunction and hypotension despite optimal volume resuscitation. Refractory septic shock carries a very high rate of mortality and is associated with ischemic and arrhythmogenic complications from high dose vasopressors.

Is it possible to recover from traumatic brain injury and a Glasgow coma scale score of 3 at emergency department presentation?

Introduction: A Glasgow Coma Scale (GCS) score of 3 on presentation in patients with traumatic brain injury (TBI) portends a poor prognosis. Consequently, there is often a tendency to treat these patients less aggressively because of low expectations for a good outcome.

Methods And Results: We performed a retrospective review of patients with TBI and a GCS score of 3.

Do All Acute Stroke Patients Receiving tPA Require ICU Admission?

Background: Limited resources warrant investigating models for predicting which stroke tissue-type plasminogen activator (tPA) patients benefit from admission to neurologic intensive care unit (neuroICU).

Methods: This model classifies patients who on day 1 of their ICU admission are predicted to receive one or more of 30 subsequent active life supporting treatments. Two groups of patients were compared: low risk monitor (LRM) (patients who did not receive active treatment (AT) on the first day and whose risk of ever receiving active treatment was ≤ 10%) and AT (patients who received at least one treatment on any day of their ICU admission).

RETRACTED: Ventricular Ectopic Beats: An Overview of Management Considerations.

Ventricular ectopic beats are commonly seen in daily clinical practice. Majority of them being asymptomatic, some can cause symptoms. In a normal heart, their occurrence is of no clinical significance.

Traumatic chyle leak: a rare complication of left internal jugular venous cannulation.

A traditional method for internal jugular vein catheterization has been through the transjugular approach. These days, ultrasound-guided cannulation is the preferred mode because of the higher success and lower complication rates. Complications associated with the transjugular approach include neck hematoma caused by carotid artery puncture, pleural puncture leading to pneumothorax and air embolism.