Synopsis of recent research by authors named "Amar B Singh"
- Amar B Singh's recent research focuses on the relationship between gut health, inflammation, and cancer, particularly in the context of inflammatory bowel disease (IBD) and colorectal cancer (CRC), revealing critical mechanisms through which gut dysbiosis and epithelial barriers contribute to these conditions.
- His studies demonstrate that alterations in proteins like claudins and markers like MASTL play significant roles in cancer progression, therapy resistance, and the intestinal environment's integrity, highlighting potential therapeutic targets to mitigate the risks of IBD and associated cancers.
- Singh's work also emphasizes the impact of psychological stress on gut health, exploring how conditions like PTSD can exacerbate inflammatory responses and alter microbiota homeostasis, suggesting an intersection between mental health and gastrointestinal disorders.*
