Virulence of geographically different Cryptosporidium parvum isolates in experimental animal model.

Cryptosporidium parvum is a coccidian parasite which causes gastrointestinal disease in humans and a variety of other mammalian species. Several studies have reported different degrees of pathogenicity and virulence among Cryptosporidium species and isolates of the same species as well as evidence of variation in host susceptibility to infection. The study aimed to investigate infectivity and virulence of two Cryptosporidium parvum “Iowa isolate” (CpI) and a “local water isolate” (CpW).

Comparative study between non lethal and lethal strains of Plasmodium yoelii with reference to its immunological aspect.

Innate immunity has an important role in the protection against malaria. To clarify the effect on non lethal and lethal strain of Plasmodium yoelii, comparison between two groups of C57BL/6 mice infected with 10(4) parasitized RBCs was performed. Liver and spleen mononuclear cells were isolated and analyzed by flow cytometry.