Publications by authors named "Amany A Bary"

Article Synopsis
  • - Pancreatic cancer is difficult to treat due to its poor blood supply and dense tissue, and current chemotherapy options are limited.
  • - Quinacrine, a repositioned drug with anticancer properties, can be delivered more effectively using novel nanoparticles made from natural fucoidan, enhanced by adding lactoferrin as a targeting ligand.
  • - The dual-targeted nanoparticles demonstrated a significant increase in anticancer effectiveness, reducing tumor volume by 68% and enhancing animal survival without causing liver toxicity, suggesting they could be a promising treatment for pancreatic cancer.
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Bone marrow-derived mesenchymal stem cells (BM-MSCs) represent a modern approach for management of chronic skin injuries. In this work, we describe BM-MSCs application versus their conditioned media (CM) when delivered topically admixed with fibrin glue to enhance the healing of chronic excisional wounds in rats. Fifty-two adult male rats were classified into four groups after induction of large-sized full-thickness skin wound: control group (CG), fibrin only group (FG), fibrin + MSCs group (FG + SCs), and fibrin + CM group (FG + CM).

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