Publications by authors named "Amany A Abo-Elnasr"

Article Synopsis
  • - This study investigated WAE1, an actinomycete from El-Hamara Lake, Egypt, for its potential to produce bioactive metabolites that could lead to new therapeutic treatments.
  • - WAE1 showed strong antimicrobial activity against certain bacteria, as well as notable antioxidant and moderate anti-inflammatory effects.
  • - The unique environmental conditions of El-Hamara Lake, characterized by high salinity and alkalinity, enhance the potential of WAE1 as a source of bioactive compounds, making it a promising subject for further research.
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This study investigates quercetin complexes as potential synergistic agents against the important respiratory pathogen Streptococcus pneumoniae. Six quercetin complexes (QCX1-6) were synthesized by reacting quercetin with various metal salts and boronic acids and characterized using FTIR spectroscopy. Their antibacterial activity alone and in synergism with antibiotics was evaluated against S.

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Isolation of novel bioactive metabolites from Streptomyces strains is a promising source for drug discovery. However, conventional screening approaches have limitations in identifying new leads due to redundant discoveries. Optimization of culture conditions is important but traditionally optimized one factor at a time, failing to consider interactions.

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