Publications by authors named "Amany A Abdellatif"
Article Synopsis
- - The study aimed to investigate how proton pump inhibitors (PPIs), specifically lansoprazole, affect kidney health in the context of diabetic nephropathy (DN), especially related to the process of autophagy, which is crucial for cellular maintenance.
- - Male CD1 albino mice were used to evaluate the effects of lansoprazole, metformin, and enalapril, both individually and in combination, on kidney function and autophagy markers after inducing diabetes through a specific method.
- - Findings showed that lansoprazole worsened kidney function and increased markers of autophagy impairment, while metformin and enalapril improved kidney health and glycemic control, but this was negatively impacted when
Background: In photoaging, the accumulation of ultraviolet (UV)-induced oxidative damage leads to the characteristic hallmarks of aging. Here arises the importance of autophagy as a cellular degradation process that cleans the cells of defective or aged organelles and macromolecules, thus maintaining cellular homeostasis. In spite of this, the exact impact of autophagy in photoaging is still elusive.
View Article and Find Full Text PDF