Publications by authors named "Amano Y"

Endosalpingiosis occurs in relatively young women. The incidence of endosalpingiosis exceeds that of other diseases affecting female tissues. As endosalpingiosis is a benign tumor, several women with endosalpingiosis are asymptomatic.

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Background: Underground research laboratories (URLs) provide a window on the deep biosphere and enable investigation of potential microbial impacts on nuclear waste, CO and H stored in the subsurface. We carried out the first multi-year study of groundwater microbiomes sampled from defined intervals between 140 and 400 m below the surface of the Horonobe and Mizunami URLs, Japan.

Results: We reconstructed draft genomes for > 90% of all organisms detected over a four year period.

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Although microvascular decompression (MVD) is a reliable treatment for hemifacial spasm (HFS), delayed postoperative relief is one of its main issues. We previously evaluated the morphology of the lateral spread response (LSR) and reported the correlation between delayed relief after MVD and polyphasic morphology of the LSR. The purpose of this study was to investigate the correlation between the morphology of the LSR with stimulation of the temporal and mandibular branches of the facial nerve and delayed relief of persistent HFS after MVD.

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We herein report three patients with Fontan-associated liver disease (FALD) who developed hepatocellular carcinoma (HCC). All three patients had very high serum alpha-fetoprotein (AFP) concentrations, and their HCCs were located in the peripheral areas of the liver. To identify the characteristics of FALD-HCC, we reviewed previously published case reports that included descriptions of imaging.

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Article Synopsis
  • The study focuses on analyzing the polyphenol content, specifically free flavonoids, in the bran of a new red sorghum variety (RILN-156) compared to other commercial varieties, using a process that removes the bran.
  • Various methods, including colorimetric techniques and advanced metabolomics (LC/MS and CE/MS), were used to quantify different polyphenolic components and identify 19 flavonoids, with galangin and daidzein being the most abundant.
  • The results indicated that RILN-156 has a higher concentration of polyphenolic content and antioxidant capacity than the other varieties, suggesting its potential for industrial use and further health-related research.
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Purpose: The breast shape differs between the prone position in breast magnetic resonance imaging (MRI) and the supine position on an operating table. We sought to determine the relationship between patient position-induced changes on prone and supine MRI in breast shape and mammographic breast density or thickness.

Materials And Methods: We evaluated data from 68 women with 69 breast cancers in this retrospective observational study.

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For systematic monitoring of radioactive nuclides in marine products, this study aimed at streamlining and simplifying the analysis method for the prominent radioisotope, strontium-90 (90Sr). The DGA chelate solid-phase extraction technique was employed for enhanced efficiency. The study focused on optimizing the necessary pretreatment procedures while minimizing the steps involving HNO3 leaching.

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By exciting a series of 1s^{2} ^{1}S_{0}→1snp^{1}P_{1} transitions in heliumlike nitrogen ions with linearly polarized monochromatic soft x rays at the Elettra facility, we found a change in the angular distribution of the fluorescence sensitive to the principal quantum number n. In particular it is observed that the ratio of emission in directions parallel and perpendicular to the polarization of incident radiation increases with higher n. We find this n dependence to be a manifestation of the Hanle effect, which served as a practical tool for lifetime determinations of optical transitions since its discovery in 1924.

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A thiosulfate-oxidizing bacterium, sp. strain V2501, was isolated from groundwater collected in a terrestrial deep subsurface environment. This strain was capable of chemolithoautotrophic growth on CO and thiosulfate.

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Breastfeeding practices during hospitalisation may influence subsequent breastfeeding practices; however, this association has not been well studied in Japan. Therefore, we aimed to examine the association between exclusive breastfeeding (EBF) during hospitalisation and that under 6 months and describe the change in breastfeeding patterns from the first to the sixth month based on the breastfeeding status during hospitalisation. This nationwide cross-sectional internet survey conducted in Japan included 1,433 postpartum women of < 6 months who underwent live singleton deliveries between January 2021 and August 2021.

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Clinical diagnosis of intraoperative transfusion anaphylaxis using clinical symptoms is challenging and should be made carefully, as an incorrect clinical diagnosis can exacerbate surgical bleeding secondary to stopping a clinically indicated blood transfusion. The timing of onset of anaphylaxis to start of transfusion may be the key to correctly diagnosing intraoperative transfusion anaphylaxis clinically. However, the reliability of this measure remains unknown.

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Lignin-carbohydrate complexes (LCCs) present a considerable hurdle to the economic utilization of lignocellulosic biomass. Glucuronoyl esterase (GE) is an LCC-degrading enzyme that catalyzes the cleavage of the cross-linkages between lignin and xylan in LCCs. Benzyl-d-glucuronate (Bn-GlcA), a commercially available substrate, is widely used to evaluate GE activity assays.

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Background: There is an increased risk of acute exacerbation of idiopathic interstitial pneumonia when treating patients with advanced non-small cell lung cancer with idiopathic interstitial pneumonia. There is no standard optimal treatment regimen for patients with lung cancer complicated with idiopathic interstitial pneumonia. We aimed to evaluate the efficacy and safety of carboplatin (CBDCA), bevacizumab (Bmab) and weekly paclitaxel (PXT) in patients with idiopathic interstitial pneumonia.

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Although microvascular decompression (MVD) is a reliable treatment for hemifacial spasm (HFS), postoperative delayed relief is one of its main issues. We previously evaluated the morphology of the lateral spread response (LSR) and reported correlation between delayed relief after MVD and polyphasic morphology of the LSR. This study aimed to investigate the morphology of LSR and the course of recovery of the compound motor action potential (CMAP), to better understand the pathophysiology of delayed healing of HFS.

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Article Synopsis
  • The skin-prick and intradermal tests are key methods for diagnosing perioperative anaphylaxis, with the intradermal test being more sensitive but potentially painful for children.* -
  • In a case study, an 8-year-old boy with autism experienced anaphylaxis during surgery; the intradermal test was conducted under general anesthesia to avoid causing distress from multiple injections.* -
  • The test identified piperacillin as the allergenic trigger, allowing the boy to undergo safe surgery afterward without the same anesthetic agent.*
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Knee osteoarthritis (OA) with extra-articular deformity (EAD) is a rare condition for which achieving accurate alignment with total knee arthroplasty (TKA) is difficult. Extra-articular corrective osteotomy may be necessary for severe deformities. A 76-year-old man underwent TKA for knee OA with EAD due to malunion after fractures of the femur and tibia.

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Background: Knee arthroplasty is a well-established surgery with good clinical outcomes. However, periprosthetic fractures and aseptic loosening negatively impact clinical outcomes, and osteoporosis is one of the causes of such complication. Osteoporosis is usually evaluated by bone mineral density of the lumbar spine and hip using dual-energy X-ray absorptiometry (DXA).

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Background: Cancer utilizes immunosuppressive mechanisms to create a tumor microenvironment favorable for its progression. The purpose of this study is to histologically characterize the immunological properties of the tumor microenvironment of oral squamous cell carcinoma (OSCC) and identify key molecules involved in the immunological microenvironment and patient prognosis.

Methods: First, overlapping differentially expressed genes (DEGs) were screened from OSCC transcriptome data in public databases.

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A 61-year-old man presented to our hospital with a chief complaint of chronic cough. He was diagnosed with lung squamous cell carcinoma at clinical stage cT2aN3M1a. He received chemotherapy up to the fourth line, but both the primary tumor and lymph node metastases increased in size.

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Article Synopsis
  • - Methanoperedens, a type of archaea, helps reduce methane emissions and hosts unique extrachromosomal genetic elements (ECEs) called Borgs, which influence their activity; however, the diversity of these ECEs has not been thoroughly explored.
  • - New research identifies small linear ECEs, circular viruses, and other unclassified ECEs associated with Methanoperedens, with linear ECEs sharing characteristics with Borgs, prompting the term "mini-Borgs."
  • - Mini-Borgs show significant genetic diversity across at least five groups and are linked to various Methanoperedens viruses, suggesting a complex network of genetic exchange that may affect the functioning and evolution of their host
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Metabolic dysfunction-associated steatotic liver disease (MASLD), previously known as non-alcoholic fatty liver disease, encompasses steatosis and metabolic dysfunction-associated steatohepatitis (MASH), leading to cirrhosis and hepatocellular carcinoma. Preclinical MASLD research is mainly performed in rodents; however, the model that best recapitulates human disease is yet to be defined. We conducted a wide-ranging retrospective review (metabolic phenotype, liver histopathology, transcriptome benchmarked against humans) of murine models (mostly male) and ranked them using an unbiased MASLD 'human proximity score' to define their metabolic relevance and ability to induce MASH-fibrosis.

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Article Synopsis
  • Primary testicular lymphoma (PTL) is rare, and patients often receive radiation therapy to the contralateral testis to prevent relapse after achieving remission.
  • A 76-year-old man treated for PTL developed a new mass in the glans penis 6.5 years later, prompting investigation into whether it was a relapse or a new cancer.
  • Genomic analysis revealed that the penile lymphoma shared genetic similarities with the original PTL, confirming it as a relapse, marking it as the first reported case of PTL returning in the glans penis.
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Trehalose is known to protect enzymes from denaturation. In the present study, we observed promotion of apple polyphenol oxidase (PPO) inactivation in a trehalose solution with thermal treatment. Crude PPO from Fuji apple was mixed with either sucrose or trehalose solutions, then the samples treated at 25 or 65 °C.

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