Publications by authors named "Amani Olaiwan"
Background: Recent identification of STAT3 mutations in autosomal dominant (AD) hyper-IgE syndrome (HIES) has improved the clinical, genetic, and molecular classification of the HIES.
Objective: We sought to characterize the cutaneous signs observed in molecularly diagnosed AD-HIES.
Methods: We conducted a retrospective study of 21 patients with AD-HIES and confirmed STAT3 mutations, treated at Necker-Enfants Malades Hospital, Paris, France.
Article Synopsis
- Bisphosphonates, like ibandronate, are used to treat bone diseases but can cause rare skin reactions ranging from mild rashes to severe conditions like toxic epidermal necrolysis.
- Two new cases of skin lesions were observed after oral ibandronate intake, confirmed with positive prick tests and histological analysis, but did not recur after switching to another bisphosphonate.
- There is a wide variety of cutaneous reactions associated with bisphosphonates, which can be misdiagnosed due to their polymorphic nature and the potential for delayed onset.