Publications by authors named "Amani Mahroug"

Article Synopsis
  • A systematic review and meta-analysis were conducted to evaluate the effectiveness and safety of naltrexone as a treatment for amphetamine-type stimulant use disorder (ATSUD) using data from several medical databases.
  • Five randomized placebo-controlled trials involving 419 participants were analyzed, showing no significant difference in outcomes such as reductions in stimulant use, treatment retention, or cravings between naltrexone and placebo groups.
  • The study concluded that there is insufficient evidence to support the use of naltrexone alone for treating ATSUD, highlighting the need for more research to find effective pharmacotherapies alongside psychosocial treatments.
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Cannabidiol (CBD) has been proposed to have a therapeutic potential over a wide range of neuropsychiatric disorders, including substance use disorders. Pre-clinical evidence suggests that CBD can increase anandamide (AEA) plasma concentration, possibly mediating some of its therapeutic properties. Whether CBD exerts such an effect on AEA in individuals with cocaine use disorder (CUD) remains unknown.

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Background: Our societies are facing mental health challenges, which have been compounded by the Covid-19. This event led people to isolate themselves and to stop seeking the help they needed. In response to this situation, the Health and Recovery Learning Center, applying the Recovery College (RC) model, modified its training program to a shorter online format.

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