Publications by authors named "Amanda-Jane Ramirez"

Background: UK policy aims to improve cancer outcomes by promoting early diagnosis, which for many haematological malignancies is particularly challenging as the pathways leading to diagnosis can be difficult and prolonged.

Methods: A survey about symptoms was sent to patients in England with acute leukaemia, chronic lymphocytic leukaemia (CLL), chronic myeloid leukaemia (CML), myeloma and non-Hodgkin lymphoma (NHL). Symptoms and barriers to first help seeking were examined for each subtype, along with the relative risk of waiting >3 months' time from symptom onset to first presentation to a doctor, controlling for age, sex and deprivation.

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Over the last few years, there has been growing international concern about the risk of overdiagnosis in breast screening and about how to communicate this to women. There has also been an increasing policy drive to provide people with information to enable them to make an informed choice about screening. In response to this, a novel approach to developing the information about cancer screening has been adopted in England.

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Background: Some young women experience delays in diagnosis of cervical cancer, but little research about ways of studying these delays has been published. A major challenge is that gynaecological symptoms are common in young women, but cervical cancer is rare. This study describes the development and testing of a measure for studying delays in diagnosis in young women with cervical cancer.

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Objectives: Older women are more likely to delay presentation with breast cancer, which contributes to poorer survival. We evaluated a written intervention that was designed to provide women with the knowledge, motivation, confidence and skills to present promptly with breast cancer symptoms.

Methods: We assessed acceptability and understanding of the intervention by interviewing 43 women.

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Background: Cancer multidisciplinary teams (MDTs) are established in many countries but little is known about how well they function. A core activity is regular MDT meetings (MDMs) where treatment recommendations are agreed. A mixed methods descriptive study was conducted to develop and test quality criteria for observational assessment of MDM performance calibrated against consensus from over 2000 MDT members about the "characteristics of an effective MDT".

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Article Synopsis
  • Menopausal symptoms are prevalent and troublesome for breast cancer patients undergoing adjuvant treatment, with a study involving 113 women highlighting the serious impact on their quality of life.
  • Women reported high rates of hot flushes (80%) and night sweats (72%), which were linked to increased anxiety, sleep issues, and poorer emotional and social well-being.
  • Despite various treatments attempted, many lacked efficacy; however, a strong preference for non-medical options like vitamins, herbal remedies, and cognitive behavioral therapy (CBT) was noted, with CBT showing promise for reducing symptoms but needing further research in this specific group.
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