Publications by authors named "Amanda Wall"
The high cost and negative environmental impact of precious metal catalysts has led to increased demand for nonprecious alternatives for widely practiced reactions such as the Suzuki-Miyaura coupling (SMC). Ni-catalyzed versions of this reaction have failed to achieve high reactivity with Lewis-basic arylboron nucleophiles, especially pinacolboron esters. We describe the development of (PPhMe)NiCl as an inexpensive and air-stable precatalyst that addresses this challenge.
View Article and Find Full Text PDFChildren with or at risk of faltering growth require nutritional support and are often prescribed oral nutritional supplements (ONS). This randomised controlled trial investigated the effects of energy-dense paediatric ONS (2.4 kcal/ml, 125 ml: cONS) versus 1.
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- The study aimed to understand how the size of abdominal aortic aneurysms (AAA) affects survival rates after a specific surgical procedure called endovascular aneurysm repair (EVAR).
- Data from 325 patients who underwent EVAR between 2003 and 2013 were analyzed, with a focus on mortality at 3, 5, and 10 years while considering factors like age and other health conditions.
- Findings indicated that AAA size ≥5.6 cm was linked to a higher risk of death within 3 years but not significantly so at 5 or 10 years, and after adjusting for other health factors, the impact of AAA size on mortality diminished.
Background: Although long-term durability and improved perioperative outcome of endovascular abdominal aortic aneurysm (AAA) repair has been demonstrated, some studies have suggested an increased rate of secondary interventions compared with open AAA repair. More recent data suggest that rates between the two modalities may be similar. We investigated the rate of secondary intervention in patients undergoing endovascular aortic aneurysm repair (EVAR) or open AAA repair for intact AAA and the effect of secondary intervention on long-term mortality in these two groups of patients.
View Article and Find Full Text PDFGlycosidases perform a wide range of functions in physiology and pathology, and are potential targets for the treatment of diseases such as influenza, cancer, AIDS and diabetes. This paper reports a convenient discontinuous colourimetric assay for the measurement of glycosidase activity. The assay utilises 4-nitrophenyl- substrates and quantities of product are determined by measuring absorbance at 405 nm.
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