Publications by authors named "Amanda Trimble"
In collaboration with the American College of Veterinary Pathologists.
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- This study investigates the safety and efficacy of delivering chemotherapy directly into the fourth ventricle of nonhuman primates to treat malignant tumors.
- It involved administering MTX110, a soluble panobinostat solution, through catheters in rhesus macaque monkeys with different infusion timelines to observe drug distribution and neurological effects.
- Results showed no serious side effects, maintained brain structure, and significantly higher levels of panobinostat in the CSF of the fourth ventricle compared to lumbar CSF, indicating effective localized delivery.
Background: Streptococcus equi subspecies equi infection elicits M protein antibody titers in equids. Interpretation of titers is not generally accepted.
Hypothesis: The magnitude of S.
Leptospirosis is a worldwide veterinary and public health concern, and well recognized infectious disease of horses. Seroprevalence rates vary with geography, but many studies have confirmed a high exposure rate. The correlation between seropositivity and shedding status has not been made in horses, however.
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