Publications by authors named "Amanda S A Witt"

Article Synopsis
  • This study analyzes the GC% content in viruses from the phylum Nucleocytoviricota to understand their biology, evolution, and relationships with hosts.
  • The research compares GC% across different viral families, finding some with similar values, while others show significant variation, possibly due to adaptations and evolutionary pressures.
  • Additionally, it highlights the implications of gene position and history, suggesting that certain genes may reveal unique evolutionary paths, indicating a diversity that can inform future research.
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In early May 2022, the first worldwide monkeypox virus (MPXV) outbreak was reported, with different clinical aspects from previously studied human monkeypox infections. Despite monkeypox medical importance, much of its biological aspects remain to be further investigated. In the present work, we evaluated ultrastructural aspects of MPXV asynchronous infections in Vero cells by transmission electron microscopy (TEM).

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Article Synopsis
  • The discovery of giant viruses has significantly expanded our understanding of the virosphere and revealed complex genomes and large particle sizes in viruses.
  • This year marks the tenth anniversary of studies on giant viruses in Brazil, where unique biomes like the Amazon and Atlantic forest have been explored for viral research.
  • The article highlights the contributions of Brazilian research groups in uncovering the diversity and uniqueness of giant viruses found in these rich ecosystems.
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Several research groups have studied the components produced by the venom gland of the scorpion Tityus serrulatus, which has one of the most lethal venoms in the world. Various methodologies have been employed to clarify the complex mechanisms of action of these components, especially neurotoxins and enzymes. Transcriptomes and proteomes have provided important information for pharmacological, biochemical, and immunological research.

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