Thyroxine, levothyroxine, and thyroxine complexed into cyclodextrin changed animal behavior, oxygen consumption, and photopic electroretinogram of Colossoma macropomum.

The toxic effects of thyroxine (TF), levothyroxine (L-T), and thyroxine complexed into β-cyclodextrin (β-CD-T) on the biological parameters of tambaqui (Colossoma macropomum) were evaluated. The animals were exposed to a chronic toxicity test based on concentrations of influent (60 ng/L) for 2 months. Weight, total length, animal behavior, oxygen consumption, photopic electroretinogram (ERG), and the Flicker exam were evaluated.

The complexation of steroid hormones into cyclodextrin alters the toxic effects on the biological parameters of zebrafish (Danio rerio).

The objective of this study was to evaluate the toxic effects of progesterone (PF) and estradiol (EF) and the effect of these steroid hormones complexed into cyclodextrins, commercially available drugs, such as micronized progesterone (PM) and transdermal estradiol (ET), and evaluate them as endocrine disruptors through biological parameters of Danio rerio. An acute toxicity test was performed with hormones using D. rerio embryos according to OECD 236 guidelines.

Microstructural evaluation by confocal and electron microscopy in thrombi developed in central venous catheters.

Objective: Evaluating thrombi microstructure developed in central venous catheters using confocal and electron microscopy.

Method: An experimental, descriptive study carrying out a microstructural evaluation of venous thrombi developed in central venous catheters using Scanning Electron Microscopy and Confocal Laser Scanning Microscopy.

Results: A total of 78 venous catheters were collected over a period of three months.

Acute and chronic toxicity of the benzoylurea pesticide, lufenuron, in the fish, Colossoma macropomum.

Lufenuron is a benzoylurea insecticide that interfere in chitin synthesis in insects. Although lufenuron is widely used in agriculture and aquaculture, rare are studies described that relates to possible toxic effects in fish. This work aimed to evaluate acute and chronic toxic effects of benzoylurea pesticide (lufenuron) on biological parameters of Colossoma macropomum (Tambaqui).